cancer in dogs |

Atrial septal defect* is a hole in the division between the heart atria (upper chambers of the heart). It is an uncommon abnormality in dogs. Most are not clinically significant, but large defects can cause right heart failure and exercise intolerance. Standard Poodles are the most common breed diagnosed with ASD in the USA.[49]
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10. Kidney disease: Kidney disease is common in senior cats, but also seen in cats and dogs of all ages. It can be congenital or develop as the pet ages. While cats with kidney disease can be treated and kept healthy for several years in most cases, dogs typically deteriorate more quickly. Kidney health is typically evaluated with annual bloodwork at your veterinarian.
Genetics and environmental factors also play a role in cancer development. Some credit the uptick in canine cancer rates to dogs simply living longer with better health care options. Other blame dog “junk” food for the rise, with brand-name foods using ingredients thought to cause cancer. Check the labels and avoid BHT, BHA, and ethoxyquin.
Collie eye anomaly (CEA) is a congenital, inherited, bilateral eye disease of dogs involving the retina, choroid, and sclera. It can be a mild disease or cause blindness. It is known to occur in Smooth and Rough Collies, Shetland Sheepdogs, Australian Shepherds, Border Collies, and Nova Scotia Duck Tolling Retrievers.[62]
Overdoses of vitamins can be harmful in dogs. As an example, calcium in excess can cause bone problems, especially in the large-breed dogs. Over-supplementation of vitamins A and D can cause vitamin toxicity in dogs.[68] Excess vitamin A can cause dehydration, joint pain and can also harm the blood vessels, while too much vitamin D can cause muscular atrophy, or loss of appetite.

Alabama rot dog disease is on the rise once again in the UK, but how big a threat is it to your dog? Here is our expert guide explaining what it is, how to spot the signs and what you can do to protect your dog from catching this deadly disease. 
Older, small breeds of dogs are prone to congestive heart failure due to degeneration of the mitral valve. This condition is known to be inherited in Cavalier King Charles Spaniels. Degenerative valve disease is the most common form of heart disease in dogs.[23] Mitral insufficiency leads to turbulent blood flow and increased pressure in the left atrium. This causes increased pressure in the pulmonary blood vessels and pulmonary edema (a build-up of fluid in the lungs). Decreased output of blood by the left ventricle causes the body to compensate by increasing sympathetic tone and activating the renin–angiotensin–aldosterone system (RAAS). Increased sympathetic tone leads to increased peripheral vascular resistance and increased heart rate and contractility of the heart muscle. Chronic elevation of sympathetic tone damages the heart muscle. Activation of the RAAS results in increased retention of water and sodium by the kidneys, vasoconstriction, and other effects that result in increased blood volume. It also results in an increase in diastolic pressure and leads to pulmonary edema. Treatment for congestive heart failure has historically focussed on two types of drugs that address these concerns: diuretics (especially furosemide), which decrease blood volume, and ACE inhibitors, which interrupt the RAAS. Recently, pimobendan – which increases the force with which the heart muscle contracts, and is also a vasodilator – is being more widely used in the treatment of congestive heart failure caused by valvular disease. A major veterinary study, called the QUEST study (QUality of life and Extension of Survival Time), published in September 2008 found that dogs with congestive heart failure receiving pimobendan plus furosemide had significantly better survival outcomes than those receiving benazepril (an ACE inhibitor) plus furosemide.[24] However, ACE inhibitors and pimobendan have different mechanisms of action, and many veterinary cardiologists recommend they be used concurrently. Within the past decade, a new surgical technique has been developed for mitral valve repair that replaces or strengthens the mitral valve chords with polytetrafluoroethylene (PTFE) prostheses and tightens the mitral valve ring to reduce or eliminate regurgitation.[25][26][27][28]
Sensitivity to anaesthesia can occur in any breed, but sighthounds have been the breeds most documented to have anesthetic concerns. Sighthounds are known to have prolonged recovery times from ultra short-acting thiobarbiturates such as thiopental.[164]
Pemphigus is an uncommon autoimmune skin disease. The most common form in dogs is pemphigus foliaceus, which manifests as erosions and crusting of the skin and mucocutaneous junctions. Pemphigus vulgaris is more rare and manifests as blister-like lesions in the mouth and at mucocutaneous junctions. Bullous pemphigoid is most commonly seen in Dobermanns and Collies and appears as a scald-like lesion of the groin.[81]
Luxating patella is a medial or lateral displacement of the patella, or kneecap. It is strongly suspected to be inherited, but can also result from trauma.[36] It is more common in smaller breeds of dogs [1]
Congenital vertebral anomalies, including butterfly, block, and transitional vertebrae, and hemivertebrae, are a collection of malformations of the spine in animals. Most are not clinically significant, but they can cause compression of the spinal cord by deforming the vertebral canal or causing instability.[6]
  Many studies show the health benefits of dog ownership. Dogs not only provide comfort and companionship, but several studies have found that dogs decrease stress and promote relaxation. Dogs have positive impacts on nearly all life stages. They influence social, emotional, and cognitive development in children, promote an active lifestyle, and have even been able to detect oncoming epileptic seizures or the presence of certain cancers. But for all the positive benefits of keeping dogs, pet owners should be aware that dogs can carry germs that make people sick.
Animal testing Baiting Breed-specific legislation Dog attack Dog park Human-canine bond Dog sports Dog walking Dog daycare Dog grooming Famous dogs Therapy Fear of dogs Dog licence Dog meat Dog food dog biscuit 2007 recalls Dogs in religion Origin
People who are infected with brucellosis will usually become sick within 6-8 weeks of exposure. Sick people will have flu-like symptoms that last 2-4 weeks. Sometimes brucellosis can become a chronic illness that can be difficult to treat.
Although Echinococcus invades many different organs of the body, most people who are infected with the disease will not have any signs of illness for years. Symptoms start when the slow-growing cysts become large enough to press on the organs they have invaded. The tapeworms grow slowly in several different organs of the body, most commonly the liver and lungs.
The dog tapeworm is a parasite spread to dogs, cats, and people through the ingestion of infected fleas. This parasite is common but rarely causes illness in pets or people. Infections with Dipylidium caninum can sometimes be detected by finding rice-like segments of the tapeworm crawling near the anus or in fresh bowel movements. In severe infections, pets can lose weight and have mild diarrhea.
Jump up ^ Rebar, A. H.; MacWilliams, P. S.; Feldman, B. F.; et al. (2005). “Platelets: Overview, Morphology, Quantity, Platelet Function Disorders (Thrombocytopathia or Thrombopathia)”. A Guide to Hematology in Dogs and Cats. Retrieved 2006-12-16.
Pancreatitis*, or inflammation of the pancreas, is common in dogs. It is most commonly seen in middle-aged and older overweight dogs. Miniature Schnauzers are predisposed. Contributing factors include diabetes, hyperlipidemia, obesity, and dietary indiscretion. Signs include vomiting, diarrhea, abdominal pain, lethargy, and anorexia.[144]
Leptospirosis is a zoonotic disease caused by bacteria of the genus Leptospira. Humans and dogs become infected through contact with water, food, or soil containing urine from infected animals. This may happen by swallowing contaminated food or water or through skin contact, especially with mucosal surfaces, such as the eyes or nose, or with broken skin. In dogs, transmission most commonly occurs by drinking puddle, pond, or ditch water contaminated by urine from infected wildlife such as squirrels or raccoons. The liver and kidney are most commonly damaged by leptospirosis. Vasculitis can occur, causing edema and potentially disseminated intravascular coagulation (DIC). Myocarditis, pericarditis, meningitis, and uveitis are also possible sequelae.[5]
Pericardial effusion* is a collection of fluid in the pericardium. It is usually serosanguinous (bloody fluid). Serosanguinous accumulation can be caused by cancer, usually hemangiosarcoma or a heart base tumor, idiopathic pericarditis. Rare causes include trauma, clotting disorders, and left atrial rupture. Serous accumulation is rare and caused by heart failure, peritoneopericardial diaphragmatic hernias, uremia, pericardial cysts, or hypoalbuminemia. Rarely pericardial effusion can be caused by infection and consist of pus. An echocardiogram should be done prior to draining the fluid, if possible, to identify the cause (e.g., tumor). Drainage of the fluid (pericardiocentesis) relieves the clinical signs and, in the case of idiopathic pericarditis, can be curative.[49]
I love playing with my family. Running, jumping, swimming: it’s all great. But my favorite is fetch. For some reason, when we play fetch with my Humunga Stache, my family seems to have even more fun than usual. There’s lots of laughing and they take extra pictures of me. I don’t know why, but if it makes them happy, it’s fine with me!
Jump up ^ Rijnberk, A, Eigenmann, JE, Belshaw, BE, Hampshire, J, Altszuler, N. (1980). “Acromegaly associated with transient overproduction of growth hormone in a dog”. Journal of the American Veterinary Medical Association. Journal-American Veterinary Medical Association. 177 (6): 534–7. PMID 7440347.
Kennel cough is an infectious respiratory disease which can be caused by one of several viruses or by Bordetella bronchiseptica. It most commonly occurs in dogs in close confinement such as kennels.[14]
People who become infected with leptospirosis might not have any signs of the disease. Others will have nonspecific flu-like signs within 2-7 days after exposure. These symptoms usually resolve without medical treatment, but can reappear and lead to more severe disease.
Masticatory muscle myositis (MMM) is an inflammatory disease in dogs affecting the muscles of the jaw. Signs include swelling of the jaw muscles and pain on opening the mouth. In chronic MMM there is atrophy of the jaw muscles, and scarring of the masticatory muscles due to fibrosis may result in inability to open the mouth (trismus).[6]
As the name suggests, an infected mosquito injects a larva into the dog’s skin, where it migrates to the circulatory system and takes up residence in the pulmonary arteries and heart, growing and reproducing to an alarming degree. The effects on the dog are quite predictable, cardiac failure over a year or two, leading to death. Treatment of an infected dog is difficult, involving an attempt to poison the healthy worm with arsenic compounds without killing the weakened dog, and frequently does not succeed. Prevention is much the better course, via heartworm prophylactics which contain a compound which kills the larvae immediately upon infection without harming the dog. Often they are available combined with other parasite preventives.
Bloat can affect any dog at any age but there are breeds more susceptible to it: usually large breed, deep-chested dogs like Great Danes, German shepherds, boxers, Labrador retrievers, bloodhounds, and weimaraners. Mid-size and smaller dogs aren’t much at risk, with the exception of basset hounds and dachshunds, who also have long, broad chests.
Although a certain form of diabetes—the type found in dogs less than a year of age—is inherited, proper diet and regular exercise can go a long way to avoid the development of diabetes. Aside from other negative effects, obesity is known to contribute to insulin resistance.
Coccidioidomycosis* is a fungal disease caused by Coccidioides immitis or Coccidioides posadasii that affects a variety of species, including dogs. In dogs signs of primary pulmonary disease include a cough, fever, weight loss, anorexia, and lethargy. Disseminated disease occurs when the fungus has spread outside of the lungs and may include clinical signs such as lameness, pain, seizures, anterior uveitis, and localized swelling.[17] Diagnosis of Valley Fever may include multiple tests, including serology and radiology. According to a study performed in the Tucson and Phoenix area, 28% of dogs will test positive for exposure to the fungus by two years of age, but only 6% of the dogs will be ill with clinical disease.[18] There is an increased risk of infection associated with amount of time spent outdoors, a larger roaming space accessed by the dog, and increasing age.[19]
Note: Do not attempt to handle or capture a wild animal who is acting strangely (i.e., a nocturnal animal who is out during the day, an animal who acts unusually tame). Report the animal to local animal control officers as soon as possible.
Complications include dehydration, secondary infections, sepsis and a condition in which part of the intestine slips into the part below it (called intussusception). CPV also can damage the spleen. Dogs that have another health condition are at increased risk for developing severe complications and illness.
Anal fistulae*, known as perianal fistulae in dogs, are most common in German Shepherd Dogs. They are characterized by draining tracts in the skin around the anus. The cause is unknown. Surgical treatment is common, but recently use of cyclosporine in combination with ketoconazole has been shown to be effective.[143]

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