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Polyneuropathy is a collection of peripheral nerve disorders that often are breed-related in dogs. Polyneuropathy indicates that multiple nerves are involved, unlike mononeuropathy. Polyneuropathy usually involves motor nerve dysfunction, also known as lower motor neuron disease.
Jump up ^ Freeman, LM; Abood, SK; Fascetti, AJ; Fleeman, LM; Michel, KE; Laflamme, DP; Bauer, C; Kemp, BL; Van Doren, JR; Willoughby, KN (15 August 2006). “Disease prevalence among dogs and cats in the United States and Australia and proportions of dogs and cats that receive therapeutic diets or dietary supplements”. J. Am. Vet. Med. Assoc. 229 (4): 531–4. doi:10.2460/javma.229.4.531. PMID 16910851.
Jump up ^ Eubig P, Brady M, Gwaltney-Brant S, Khan S, Mazzaferro E, Morrow C (2005). “Acute renal failure in dogs after the ingestion of grapes or raisins: a retrospective evaluation of 43 dogs (1992–2002)”. J. Vet. Intern. Med. 19 (5): 663–74. doi:10.1892/0891-6640(2005)19[663:ARFIDA]2.0.CO;2. PMID 16231710.
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This list of dog diseases is a selection of diseases and other conditions found in the dog. Some of these diseases are unique to dogs or closely related species, while others are found in other animals, including humans. Not all of the articles listed here contain information specific to dogs. Articles with non-dog information are marked with an asterisk (*).
Demodicosis, also known as demodectic mange, is caused by Demodex canis mites which live in small numbers in sebaceous glands and hair follicles. These mites can cause inflammation and hair loss, and may also lead to secondary bacterial infections such as fever, lethargy, and enlarged lymph nodes.
MRSA can be transmitted back and forth between people and animals through direct contact. In people, MRSA most often causes skin infections that can range from mild to severe. If left untreated, MRSA can spread to the bloodstream or lungs and cause life-threatening infections.
If your dog will be housed outside, provide shelter such as a doghouse for when it is cold or rainy and shade for when it is hot. Protecting your dog from the changes in weather will reduce stress and help keep it healthy.
Subaortic stenosis, or SAS, is a genetic ailment that causes a narrowing of the passage of blood between the heart and the aorta. This leads to heart problems and sometimes sudden death. It affects larger breeds such as the Newfoundland Dog and the Golden Retriever.[15] In some dogs, such as collies, the blue merle or harlequin coloring is actually the heterozygote of a partially recessive gene preventing proper development of the nervous system; therefore, if two such dogs are mated, on the average one quarter of the puppies will have severe genetic defects in their nervous systems and sensory organs ranging from deafness to fatal flaws.
Brachycephalic airway obstructive syndrome is a condition of brachycephalic (short-nosed) dogs, characterized by the presence of stenotic nares, elongated soft palate, narrow trachea, collapsed larynx, and everted laryngeal saccules. Signs include difficult and noisy breathing. Surgical options are available.[185]
Jump up ^ Cohen, Michelle, Post, Gerald S. (2002). “Water Transport in the Kidney and Nephrogenic Diabetes Insipidus”. Journal of Veterinary Internal Medicine. Journal of Veterinary Internal Medicine. 16 (5): 510–7. doi:10.1111/j.1939-1676.2002.tb02379.x. PMID 12322698. (PDF)
Cushing’s syndrome, also known as hyperadrenocorticism, is characterized by an increase in glucocorticoids secreted by the adrenal glands. About 85 percent of cases are caused by a tumor in the pituitary gland, while 15 percent are caused by an adrenal tumor. The pituitary gland produces a hormone that signals the adrenal gland to produce cortisol; a tumor can cause it to produce the adrenal-stimulating hormone even when it is not needed.[115][116] Signs include increased appetite, increased drinking and urination, a pot-bellied appearance, muscle weakness, and lethargy.[115] Cushing’s can be caused by overuse of steroid medications; in some cases, stopping the medication is enough to solve the problem.[115] Diagnosis can be difficult as there are no tests with both high sensitivity and specificity.[117] Treatments inclulde mitotane, trilostane,[118][119] ketoconazole, or selegiline.[120][121] Surgery is used in some cases of adrenal tumors.[122]
Jump up ^ Eirmann, L (2017). “Chapter 167: Antioxidants, nutraceuticals, probiotics, and nutritional supplements”. In Ettinger, SJ; Feldman, EC; Cote, E. Textbook of Veterinary Internal Medicine (8th ed.). Elsevier Health Sciences. ISBN 9780323312394.
However, there is one cause of chronic kidney disease that is preventable: dental disease. In the advanced stages of dental disease, bacteria from the dog’s gums can enter the bloodstream and damage vital organs, like the kidneys.
Jump up ^ Paciello, O.; Lamagna, F.; Lamagna, B.; Papparella, S. (2003). “Ehlers-Danlos–Like Syndrome in 2 Dogs: Clinical, Histologic, and Ultrastructural Findings” (PDF). Veterinary Clinical Pathology. 32 (1): 13–18. doi:10.1111/j.1939-165X.2003.tb00306.x. PMID 12655483. Retrieved 2007-01-01.
As the name suggests, an infected mosquito injects a larva into the dog’s skin, where it migrates to the circulatory system and takes up residence in the pulmonary arteries and heart, growing and reproducing to an alarming degree. The effects on the dog are quite predictable, cardiac failure over a year or two, leading to death. Treatment of an infected dog is difficult, involving an attempt to poison the healthy worm with arsenic compounds without killing the weakened dog, and frequently does not succeed. Prevention is much the better course, via heartworm prophylactics which contain a compound which kills the larvae immediately upon infection without harming the dog. Often they are available combined with other parasite preventives.
“Treatment is supportive, but is only successful in 20-30% of cases, which is why we’re encouraging all dog owners to use the online interactive guide to help them understand the clinical signs and confirmed locations of Alabama Rot.
^ Jump up to: a b Rand, J., Fleeman, L.; et al. (2005). “Canine and Feline Diabetes Mellitus: Nature or Nurture?”. Centre for Companion Animal Health, School of Veterinary Science, The University of Queensland, Brisbane 4072, Australia. Retrieved 25 January 2011.
This tick-borne illness is another highly preventable disease. It is caused by a bacteria transmitted by slow-feeding deer ticks that have been attached to the dog for at least 18 hours. It’s the most common of the tick-related illnesses.
Pica is an appetite for, or the behavior of eating, non-nutritive substances (e.g., sand, coal, soil, chalk, paper etc.). Pica can be dangerous to dogs, with a risk from eating dirt near roads that existed prior to the phaseout of tetraethyllead in gasoline or prior to the cessation of the use of contaminated oil (either used, or containing toxic PCBs) to settle dust. In addition to poisoning, there is a risk of gastro-intestinal obstruction or tearing in the stomach or blockage of the esophagus.
The frequency of bilateral glaucoma with a genetic base in purebred dogs is higher than in any species except humans.[22] Cataracts in dogs either have a genetic base or can also be caused by diabetes. Nuclear sclerosis resembles a cataract but is actually a normal age-related change.

Tick-borne diseases are common in dogs. Lyme disease, or borreliosis, is caused by Borrelia burgdorferi and spread by Ixodes pacificus on the West coast of the United States and by I. scapularis (deer tick) in the rest of the U.S. Signs and symptoms include fever, joint swelling and pain, lameness, and swelling of the lymph nodes. It has been diagnosed in dogs in all 48 states of the continental U.S.[7] Ehrlichia canis, which causes canine ehrlichiosis, and Rickettsia rickettsii, which causes Rocky Mountain spotted fever, are both spread by the American dog tick, Dermacentor variabilis, and the brown dog tick, Rhipicephalus sanguineous.[8]
9. Diabetes: Just like with humans, pets can develop diabetes as part of the aging process. While diabetes in cats and dogs can often be controlled by a plan of diet and exercise, some pets will require regular insulin shots.
Because of the overpopulation of dogs in some countries, puppies born to strays or as the result of accidental breedings often end up being killed in animal shelters. Spaying and neutering can also decrease the risk of hormone-driven diseases such as mammary cancer, as well as undesired hormone-driven behaviors. However, certain medical problems are more likely after neutering, such as urinary incontinence in females[71] and prostate cancer in males.[72] The hormonal changes involved with sterilization are likely to somewhat change the animal’s personality, however, and some object to spaying and neutering as the sterilization could be carried out without the excision of organs.
“Be aware of it and insist a blasto test be done early,” Picken says. “It’s a small price to pay to eliminate the possibility of a tragic outcome. I found the perfect rescue dog and was ecstatic about the thought of having so many good years with him. To go from that to the heartbreak of losing him so quickly is a pretty steep fall.”
Dental disease is very common. Calculus is the most obvious sign, but gingivitis progressing to periodontitis is what results in tooth loss. Treatment involves scaling and polishing of the teeth under general anesthesia and treatment of any periodontal disease. Prevention is very important and can be accomplished through the use of special diets or treats, brushing, and plaque prevention gels.[176]
What to look for: If your dog is vomiting, there could be any number of causes. Generally speaking, it’s best to assess your dog’s behavior leading up to the vomiting to see if there might be a more serious issue. General vomiting, initially, is normal and could have been from something your dog ate.
Rocky Mountain spotted fever* is a rickettsial disease that occurs in dogs and humans. It is caused by Rickettsia rickettsii and spread by ticks of the genus Dermacentor. Signs are similar to human disease, including anorexia, fever, and thrombocytopenia.[12]

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