degenerative joint disease in dogs |

Cushing’s syndrome, also known as hyperadrenocorticism, is characterized by an increase in glucocorticoids secreted by the adrenal glands. About 85 percent of cases are caused by a tumor in the pituitary gland, while 15 percent are caused by an adrenal tumor. The pituitary gland produces a hormone that signals the adrenal gland to produce cortisol; a tumor can cause it to produce the adrenal-stimulating hormone even when it is not needed.[115][116] Signs include increased appetite, increased drinking and urination, a pot-bellied appearance, muscle weakness, and lethargy.[115] Cushing’s can be caused by overuse of steroid medications; in some cases, stopping the medication is enough to solve the problem.[115] Diagnosis can be difficult as there are no tests with both high sensitivity and specificity.[117] Treatments inclulde mitotane, trilostane,[118][119] ketoconazole, or selegiline.[120][121] Surgery is used in some cases of adrenal tumors.[122]
Gastric dilatation volvulus, or gastric torsion and bloat, primarily affects breeds with deep, narrow chests, such as Great Danes, St. Bernards, German Shepherds, Standard Poodles and Irish Setters. The stomach twists on its supporting ligaments, sealing off the exits, and the contents begin to generate gas pressure which is very painful and rapidly causes shock and necrosis of large areas of stomach tissue. It can be fatal within a few hours. Dogs who have experienced bloat are very susceptible to recurrences. Treatment involves stabilization and abdominal surgery to tack the dog’s stomach down to prevent recurrence (gastropexy).[21]
^ Jump up to: a b Asher, L.; Diesel, G.; Summers, J.F.; McGreevy, P.D.; Collins, L.M. (2009-12-01). “Inherited defects in pedigree dogs. Part 1: Disorders related to breed standards”. Vet. J. 182 (3): 402–411. doi:10.1016/j.tvjl.2009.08.033.
Vaccinations are an important preventative animal health measure. The specific vaccinations recommended for dogs varies depending on geographic location, environment, travel history, and the activities the animal frequently engages in. In the United States, regardless of any of these factors, it is usually highly recommended that dogs be vaccinated against rabies, canine parvovirus, canine distemper, and infectious canine hepatitis (using canine adenovirus type 2 to avoid reaction). The decision on whether to vaccinate against other diseases, including leptospirosis, Lyme disease, Bordetella bronchiseptica, parainfluenza virus, and canine coronavirus, should be made between an owner and a veterinarian, taking into account factors specific to the dog.
Pasteurella is found in 50% of patients with infected dog bite wounds. Pasteurella can cause painful wound and skin infections. In more severe cases, it can cause widespread infection and might even affect the nervous system.

Because of the overpopulation of dogs in some countries, puppies born to strays or as the result of accidental breedings often end up being killed in animal shelters. Spaying and neutering can also decrease the risk of hormone-driven diseases such as mammary cancer, as well as undesired hormone-driven behaviors. However, certain medical problems are more likely after neutering, such as urinary incontinence in females[71] and prostate cancer in males.[72] The hormonal changes involved with sterilization are likely to somewhat change the animal’s personality, however, and some object to spaying and neutering as the sterilization could be carried out without the excision of organs.
Cryptosporidium can cause profuse, watery diarrhea with cramping, abdominal pain, and nausea in both animals and people. Illness in people is usually self-limiting and lasts only 2-4 days, but can become severe in people with weakened immune systems.
Corneal dystrophy is a condition characterized by bilateral, noninflammatory opacity of the cornea. It appears as grayish white lines, circles, or clouding of the cornea. Corneal dystrophy can also have a crystalline appearance.[62]
Ticks* are an external parasite of the dog and can spread diseases such as Lyme disease, Rocky Mountain spotted fever, babesiosis, and ehrlichiosis. They can also cause a neurological disorder known as tick paralysis.[32]
Jump up ^ Schütt, T; Toft, N; Berendt, M (2015). “Cognitive function, progression of age-related behavioral changes, biomarkers, and survival in dogs more than 8 years old”. Journal of veterinary internal medicine. 29 (6): 1569–77. doi:10.1111/jvim.13633. PMC 4895687 . PMID 26463980.
Patent ductus arteriosus* is one of the most common congenital heart defect in dogs around the world. It is inherited in toy and miniature Poodles, and seen commonly in German Shepherds, Pomeranians, Bichon Frises, and Malteses. Signs include a continuous heart murmur, bounding (strong) femoral pulse, tachypnea (increased breathing rate), dyspnea (labored breathing), and exercise intolerance.[49]
For most dogs, insulin injections are necessary for adequate regulation of blood glucose. Once your pet’s individual insulin treatment is established, typically based on weight, you will be shown how to give him his insulin injections at home.
Welcome to the petMD Dog Symptom Checker, where you can easily search our 1,000+ dog health articles based on the symptoms your dog is experiencing. Simply select the area of the body that is being affected and then check off any appropriate symptom(s). Articles relevant to your query will appear below.
Jump up ^ Di Marco, Viviani (2009). “Advances in the Diagnosis and Management of Canine Hyperadrenocorticism”. Proceedings of the 34th World Congress of the World Small Animal Veterinary Association. Retrieved 25 January 2011.
How to treat: Like humans, dogs should get regular insulin injections (up to twice a day) to control diabetes. Oral medications and a high-fiber diet can also work to reverse the disease and get your dog back to a healthy state.
It’s not uncommon to find your dog eating feces. Some consume their own or other dogs’ feces; others seem to prefer cat feces (which, due to the feline digestive system,[65] are high in protein and consumed by many animals in the wild) This can be harmful if the feces has any pathogens or parasites or contain excreted drugs.
Treat your dog to prevent fleas, ticks, heart worm, and other ickies from making your dog their home, says Kerns. The health effects of infestation are far worse than pesticide side effects. That said, don’t overdo it, she warns. “Use what’s absolutely necessary for your environment,” rather than mindlessly dosing your dog every month against pests it’s not like to encounter. Tip: You can check the prevalence of pests in your area at capcvet.org.
What to look for: The signs of obesity might seem obvious, but having regular weight checks is important in order to keep records of your dog’s weight over time. It is important to recognize your dog’s weight gain early to give him the best chance possible for recourse.
Vaccine reactions are adverse events which occur following vaccination, including granuloma formation, but most commonly the term vaccine reaction is used to describe a type I hypersensitivity reaction. The most common signs are facial swelling and hives, but more rarely very serious signs such as hypotension and collapse may occur.[180]
Jump up ^ Modiano J, Breen M, Burnett R, Parker H, Inusah S, Thomas R, Avery P, Lindblad-Toh K, Ostrander E, Cutter G, Avery A (2005). “Distinct B-cell and T-cell lymphoproliferative disease prevalence among dog breeds indicates heritable risk”. Cancer Res. 65 (13): 5654–61. doi:10.1158/0008-5472.CAN-04-4613. PMID 15994938.
Infectious diseases that affect dogs are important not only from a veterinary standpoint, but also because of the risk to public health; an example of this is rabies. Genetic disorders also affect dogs, often due to selective breeding to produce individual dog breeds. Due to the popularity of both commercial and homemade dog foods, nutrition is also a heavily studied subject.
Thrombocytosis* is a condition characterized by an excess of platelets. Most cases are physiologic (caused by exercise) or reactive (secondary to some cancers, blood loss, or certain drugs). Rarely the condition is caused by a primary bone marrow disorder. In this last case, the platelets may not function normally, causing the blood to not clot properly.[44]
8. Arthritis: Arthritis is often seen as a rite of passage for our older pets. They may seem slow to rise in the morning, or a bit reluctant to jump up to their favorite spot on the couch. Your veterinarian can diagnose most forms of arthritis during a routine exam, but they may also recommend an x-ray to rule out other issues or evaluate how seriously inflamed the joints are. While there is no cure for arthritis, there are joint supplements, and even treatments like acupuncture, to help keep your pet as mobile as possible for as long as possible.
Malignant histiocytosis (histiocytic sarcoma) is an aggressive cancer found primarily in certain breeds including the Bernese Mountain Dog, rottweiler, golden retriever and flat coated retriever. It is characterized by infiltration of the joints, lungs, spleen, lymph nodes, and other organs by malignant histiocytes.[6]
Most diseases that affect dogs or humans are not transferable between the two species. Diseases that can be transmitted from animals to humans are terrmed zoonoses. A well-known zoonosis is rabies, a viral infection transmitted through a bite. A common bacterial zoonosis is leptospirosis, transmitted through urine. Some of the most important zoonoses are parasitic. Zoonotic intestinal parasites transmitted through contact with feces include Toxocara canis (the canine roundworm), which causes toxocariasis, visceral larva migrans, and ocular larva migrans, and hookworms, which can cause cutaneous larva migrans. Zoonotic skin parasites include scabies, caused by the mite Sarcoptes scabiei. The most common zoonotic fungal disease is ringworm, caused in this case by Microsporum canis.

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