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Malignant histiocytosis (histiocytic sarcoma) is an aggressive cancer found primarily in certain breeds including the Bernese Mountain Dog, rottweiler, golden retriever and flat coated retriever. It is characterized by infiltration of the joints, lungs, spleen, lymph nodes, and other organs by malignant histiocytes.[6]
Primary ciliary dyskinesia* is a dysfunction of cilia, which manifests as sperm immotility and respiratory disease. Signs include nasal discharge, recurring pneumonia, and infertility. Symptoms develop soon after birth.[177]
6. Rabies: Rabies is the disease made famous in the hearbreaking scene in Old Yeller. Thankfully, the widespread use of the rabies vaccine in recent years has made its occurrence in pets in the U.S. quite rare. However, it is still present in wild animal populations, and because rabies is always fatal, it’s critical to make sure that your pets are current on their rabies vaccination.
As the name suggests, an infected mosquito injects a larva into the dog’s skin, where it migrates to the circulatory system and takes up residence in the pulmonary arteries and heart, growing and reproducing to an alarming degree. The effects on the dog are quite predictable, cardiac failure over a year or two, leading to death. Treatment of an infected dog is difficult, involving an attempt to poison the healthy worm with arsenic compounds without killing the weakened dog, and frequently does not succeed. Prevention is much the better course, via heartworm prophylactics which contain a compound which kills the larvae immediately upon infection without harming the dog. Often they are available combined with other parasite preventives.
The risk for contracting rabies runs highest if your dog is exposed to wild animals. Outbreaks can occur in populations of wild animals (most often raccoons, bats, skunks and foxes in this country) or in areas where there are significant numbers of unvaccinated, free-roaming dogs and cats.
Kanye West’s Adidas Yeezy shoe designs are typically met with Air Jordan-level fanfare when they’re released, but fans are accusing the rapper of phoning it in with his most recent design, which some say resembles Crocs.
Epilepsy in dogs can be a primary, idiopathic, inherited disorder or secondary to previous head trauma or CNS infections. Idiopathic epilepsy is commonly found in breeds such as German Shepherd Dogs, Beagles, and Dachshunds. The most common sign recurring generalized seizures beginning at a young adult age.[56]
Dog hookworms are tiny worms that can spread through contact with contaminated soil or sand. Dogs can also become infected with hookworms through accidentally ingesting the parasite from the environment or through their mother’s milk or colostrum. Young puppies are most often affected and might have dark, bloody stool and anemia. Severe infections in some puppies can lead to death.
Chocolate poisoning symptoms can last up to 72 hours. PetMD offers this chocolate toxicity meter to gauge your dog’s level of poisoning, but it’s still best to see a vet right away. For a true life story, read our post, My Dog Ate Chocolate. Here’s What Happened Next.
Jump up ^ Heuter, Kerry J.; Langston, Cathy E. (2003). “Leptospirosis: A re-emerging zoonotic disease”. The Veterinary Clinics of North America. 33 (4): 791–807. doi:10.1016/S0195-5616(03)00026-3. PMID 12910744.
Ventricular septal defect* is a hole in the division between the heart ventricles (interventricular septum). It is a congenital heart disease in dogs. There usually are no signs in dogs except for a heart murmur. However, a large defect can result in heart failure or in pulmonary hypertension leading to a right-to-left shunt.[49]
Prostate disease* in dogs includes benign prostatic hyperplasia (BPH), prostatitis (infection of the prostate), cancer, and cysts and abscesses. BPH is the most common and is found in older intact (not neutered) dogs. Signs include blood in the urine and straining to urinate and defecate. Castration is the treatment of choice.[157] Prostatis can be associated with BPH. Bacteria causing prostatitis include E. coli, Staphylococcus spp., Streptococcus spp., and Mycoplasma spp.[158]
There has been some speculation that walking dogs in particular areas of the countryside may be a contributing factor, but the Forestry Commission has yet to warn of any specific sites being dangerous, reassuring dog owners by saying “Many thousands of dogs are walked in the countryside every day and it is important to remember that only a very small number of dogs have been affected.”
Avoid bites and scratches from dogs. Dog bites might become seriously infected or might be a source of rabies. Be cautious with unfamiliar animals. Approach dogs with care, even if they seem friendly.
Fleas and ticks of various species can be acquired and brought home by a dog, where they can multiply and attack humans (and vice versa). These two parasites are particularly important to note, now that tick-borne Lyme Disease has become endemic throughout a large area, in addition to other similar diseases such as Rocky Mountain Spotted Fever. Although dogs do not seem to be as susceptible to such diseases as humans, similar rickettsial diseases have been spread by dogs to humans through such mechanisms as a dog killing an infected rabbit, then shaking itself off in the house near enough to its owners to fatally infect most of the family.
Lyme disease is a bacterial disease of people and animals transmitted by ticks. In dogs the most common signs of illness of Lyme disease are lameness, fever, reluctance to eat, lack of energy, and enlarged lymph nodes, with or without swollen, painful joints.

Insecticides* used in dogs for fleas and ticks commonly contain either organophosphates or carbamates. they can be absorbed through the skin, conjunctiva, gastrointestinal tract, and lungs. Organophosphates inhibit acetylcholinesterase irreversibly and carbamates inhibit cholinesterase reversibly. Toxicity occurs through overdosage with an appropriate product or use of an agricultural product. Signs for both include hypersalivation, vomiting, lethargy, tremors, difficulty walking, weakness, and death.[168]
Dogs in pet stores, animal shelters, and breeding kennels also are at increased risk. Overcrowding and poor sanitary conditions make it easier for the virus to spread. Certain breeds of dog (e.g., English springer spaniels, rottweilers, Doberman pinschers) and dogs that have another health condition may have a higher risk for developing severe disease.
If a lump is present, the first step is typically a needle biopsy, which removes a very small tissue sample for microscopic examination of cells. Alternately, surgery may be performed to remove all or part of the lump for diagnosis by a pathologist.
Signs of vestibular disease include head tilt, circling, nystagmus (an abnormal movement of the eyes), and difficulty or inability to stand. These clinical signs are similar to those seen in humans experiencing vertigo. Vestibular disease may have many causes. Elderly dogs are susceptible to an idiopathic (meaning due to unknown causes) form of vestibular disease commonly called “old dog vestibular disease” or idiopathic peripheral vestibular disease. The signs may improve rapidly or take a few days. Less commonly, vestibular signs can also be caused by inner ear disease, a brain tumor, a stroke, or other causes. The major risk with idiopathic peripheral vestibular disease is that the dog is often unable to eat, drink, or go outside to urinate or defecate. These cases must receive supportive therapy of intravenous fluids and nutrition; a light sedative is sometimes administered, as the dog may be very stressed by the experience.
Cancer is a class of diseases in which cells grow uncontrollably, invade surrounding tissue and may spread to other areas of the body. As with people, dogs can get various kinds of cancer. The disease can be localized (confined to one area, like a tumor) or generalized (spread throughout the body).
Eye proptosis is a condition resulting in forward displacement and entrapment of the eye from behind by the eyelids. It is a common result of head trauma in dogs. Most commonly it occurs in brachycephalic (short nosed) breeds.[62]
Jump up ^ Washabau, Robert J. (2005). “Gastrointestinal Motility Disorders of Dogs and Cats”. Proceedings of the 30th World Congress of the World Small Animal Veterinary Association. Retrieved 2007-01-14.
Liver failure* is common. Signs include vomiting, loss of appetite, weight loss, and jaundice. Causes include bacterial or viral infection, toxic insult, cancer, copper storage diseases, or it may be idiopathic.[175]
Lick granuloma also known as acral lick dermatitis, is a skin disorder in dogs resulting from an urge to lick the lower portion of the leg. The lesion from the incessant licking is a thickened, firm, oval plaque.[34]
Pica in dogs may be a sign of Immune-mediated hemolytic anemia, especially when it involves eating substances such as tile grout, concrete dust, and sand. Dogs exhibiting this form of pica should be tested for anemia with a Complete blood count including Hematocrit levels, or Packed cell volume.[46][47]

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