dog cushings disease life expectancy |

Jump up ^ Marks, Stanley L. (2003). “Bacterial Gastroenteritis in Dogs & Cats–More Common Than You Think”. Proceedings of the 28th World Congress of the World Small Animal Veterinary Association. Retrieved 2006-11-26.
People start showing signs 2-14 days after exposure; these may include fever, rash, headache, nausea, vomiting, abdominal pain, and muscle pain. RMSF can develop into a serious illness if not promptly treated.
Patent ductus arteriosus* is one of the most common congenital heart defect in dogs around the world. It is inherited in toy and miniature Poodles, and seen commonly in German Shepherds, Pomeranians, Bichon Frises, and Malteses. Signs include a continuous heart murmur, bounding (strong) femoral pulse, tachypnea (increased breathing rate), dyspnea (labored breathing), and exercise intolerance.[49]
Certain types of dog or puppy adoptions, like international pet adoption, might not be suitable for your family because of the risk for disease. This is particularly true if young children, pregnant women, or persons with weak immune systems are living in the household. Persons with weak immune systems may include the elderly or people with an illness such as diabetes or HIV/AIDS, or those undergoing chemotherapy.
Atopy* is an allergy to a substance with which the dog is not necessarily in direct contact. It is a type I hypersensitivity to a substance that is inhaled or absorbed through the skin. Up to 10 percent of dogs are affected.[77] It is common in dogs, especially seen in breeds such as Labrador Retrievers, Golden Retrievers, and Shih Tzus. The most common symptom is itching. Affected areas include the underside, the face, the feet, and the ears.[78]
Jump up ^ Authement JM, Boudrieau RJ, Kaplan PM (1989). “Transient, Traumatically Induced, Central Diabetes Insipidus in a Dog”. Journal of the American Veterinary Medical Association. Retrieved 8 April 2011.
Alabama dog rot was first identified amongst greyhounds in the state of Alabama in the 1980s. After this first flair up, the number of reported cases dwindled and as no clinical research was carried out, the disease was almost relegated to history. Because no one has been able to determine what causes the disease, it is now only recognisable by its collection of clinical symptoms.
Epilepsy in dogs can be a primary, idiopathic, inherited disorder or secondary to previous head trauma or CNS infections. Idiopathic epilepsy is commonly found in breeds such as German Shepherd Dogs, Beagles, and Dachshunds. The most common sign recurring generalized seizures beginning at a young adult age.[56]
Cushing’s syndrome, also known as hyperadrenocorticism, is characterized by an increase in glucocorticoids secreted by the adrenal glands. About 85 percent of cases are caused by a tumor in the pituitary gland, while 15 percent are caused by an adrenal tumor. The pituitary gland produces a hormone that signals the adrenal gland to produce cortisol; a tumor can cause it to produce the adrenal-stimulating hormone even when it is not needed.[115][116] Signs include increased appetite, increased drinking and urination, a pot-bellied appearance, muscle weakness, and lethargy.[115] Cushing’s can be caused by overuse of steroid medications; in some cases, stopping the medication is enough to solve the problem.[115] Diagnosis can be difficult as there are no tests with both high sensitivity and specificity.[117] Treatments inclulde mitotane, trilostane,[118][119] ketoconazole, or selegiline.[120][121] Surgery is used in some cases of adrenal tumors.[122]
“Be aware of it and insist a blasto test be done early,” Picken says. “It’s a small price to pay to eliminate the possibility of a tragic outcome. I found the perfect rescue dog and was ecstatic about the thought of having so many good years with him. To go from that to the heartbreak of losing him so quickly is a pretty steep fall.”
Because infection can potentially spread over a dog’s body and infect other animals and people, it is important that you see your vet for an accurate diagnosis if your pet is showing any signs of a skin problem.
^ Jump up to: a b Asher, L.; Diesel, G.; Summers, J.F.; McGreevy, P.D.; Collins, L.M. (2009-12-01). “Inherited defects in pedigree dogs. Part 1: Disorders related to breed standards”. Vet. J. 182 (3): 402–411. doi:10.1016/j.tvjl.2009.08.033.
Diabetes insipidus* in dogs can be central, caused by a lack of antidiuretic hormone (ADH), or nephrogenic, caused by a lack of response of the kidneys to ADH. Neither form is common. Central diabetes insipidus (CDI) is usually idiopathic, but can also be caused by head trauma[123] or tumors of the brain. Nephrogenic diabetes insipidus (NDI) can be primary (hereditary) or secondary (caused by a variety of metabolic[124] and renal diseases, including Cushing’s syndrome and pyometra). Because the disease is characterized by an inability to concentrate urine, the most common sign is increased drinking and urinating.[125][126] Treatment of CDI is to use desmopressin, a synthetic analog of ADH. Treatment of NDI is to treat the underlying cause, if any.[127]
Leishmaniasis is a protozoan disease of people and animals. It is transmitted by sandflies and is uncommon in North America. The two forms of the disease are visceral and cutaneous. The cutaneous form of leishmaniasis is most common in people and appears as one or more painless ulcers on the skin. Visceral leishmaniasis is less common and is characterized by fever, weight loss, enlarged spleen, and anemia. Dogs can develop both forms at the same time and have a variety of symptoms.
Legg-Calvé-Perthes syndrome, also known as Perthes disease or avascular necrosis of the femoral head, is characterized by a deformity of the head of the femur and hip pain. It occurs in small breed puppies.[6]
A dog who is up to date with his vaccinations and who has been bitten by a possibly rabid animal should also be given a rabies booster vaccine immediately and kept under observation (length will vary depending on your state laws).
Babesiosis* is spread by members of the family Ixodidae, or hard ticks. The two species of the genus Babesia that affect dogs are B. canis and B. gibsoni. Babesiosis can cause hemolytic anemia in dogs.[28]
How to treat: Sadly, arthritis cannot be cured, but there are things you can do to make it easier on your pet as he ages. Diet and nutrition are the two biggest things you can do to slow down the aging (and arthritis) process. Regular walks and a balanced diet of proper (age appropriate) food will keep your dog’s nutrition levels where they should be. Look for food labeled “Senior” and pay attention not to over or under feed. If your dog’s arthritis is severe, your vet can prescribe medications to alleviate the symptoms.
Tick paralysis* is a disease in dogs caused by a neurotoxin found in the saliva of female ticks. Dermacentor species predominate as a cause in North America, while Ixodes mainly causes the disease in Australia. There is a gradual onset of signs, which include incoordination progressing to paralysis, changed voice, and difficulty eating.[56]
Garlic & Onions* are toxic to dogs. Onions, Garlic, Chives – can cause the destruction of red blood cells known as Heinz body anemia, a form of hemolytic anemia. No clear quantity has been established as to the onset of the anemia. But for garlic, if your dog consumes the equivalent of 1 teaspoon of garlic for every 10 pounds of their weight (1 teaspoon for a 10-pound dog) it can destroy red blood cells. Poisonous reaction can result from raw, cooked or dried onions, garlic, chives, including those included in powdered or dehydrated forms. Avoid all foods that contain onions or onion variants (such as spaghetti sauce).
Certain breeds are prone to specific cancers. Boxers, Boston terriers and Golden Retrievers are among the breeds that most commonly develop mast cell tumors or lymphoma, while large and giant breeds like Great Danes and Saint Bernards are much more likely to suffer from bone cancer than smaller breeds.
Contact your veterinarian immediately if your dog shows any of the clinical signs mentioned on the list above. Should your dog receive a diagnosis of cancer, you may wish to consult a veterinary oncologist, often employed by specialty veterinary practices and teaching hospitals.
Jump up ^ Thrusfield, M. V; Aitken, C. G. G; Muirhead, R. H (1989). “A field investigation of kennel cough: Efficacy of vaccination”. J. Small Animal Pract. 30 (10): 550. doi:10.1111/j.1748-5827.1989.tb01471.x.
Mouse and rat poison* ingestion is common in dogs. Most rodenticides in the United States are anticoagulant by depleting Vitamin K. This type is the most frequent cause of poisoning in pets. Third generation products contain brodifacoum or bromadiolone and are toxic after a single ingestion. Signs include spontaneous and excessive bleeding internally and externally. Treatment is with Vitamin K supplementation. Other rodenticides may contain cholecalciferol which causes hypercalcemia and leads to heart and kidney problems. Newer rodenticides may contain bromethalin which causes central nervous system signs such as seizures, muscle tremors, and depression.[170]
Spondylosis*, known as spondylosis deformans in dogs, is growth of osteophytes on the ventral and lateral surfaces of the vertebral bodies. It is usually an incidental finding on radiographs and rarely causes symptoms.[39]
Tetralogy of Fallot* is a congenital heart defect in dogs that includes four separate defects: pulmonic stenosis, a ventricular septal defect, right ventricular hypertrophy, and an overriding aorta. Keeshonds and Bulldogs are predisposed. Signs include cyanosis and exercise intolerance. Polycythemia is often present and, if severe, needs to be controlled with phlebotomy or drugs to suppress red blood cell production.[49]
People become infected with dog hookworms while walking barefoot, kneeling, or sitting on ground contaminated with stool of infected animals. Hookworm larvae enter the top layers of skin and cause an itchy reaction called cutaneous larva migrans. A red squiggly line might appear where the larvae have migrated under the skin. Symptoms usually resolve without medical treatment in 4-6 weeks.

Since the disease was first detected in 2012 in the UK the number of cases of Alabama dog rot in dogs has risen. The most serious outbreak was in the New Forest region of Hampshire but there have also been reported cases in several other counties, with the most recent cases reported Gloucestershire, Monmouthshire, Devon, Dorset, Cheshire, Warwickshire, Greater Manchester and Worcestershire.
Pulmonary hypertension* is high pressure in the pulmonary artery. In dogs it can be caused by heartworm disease, pulmonary thromboembolism, or chronic hypoxemia (low oxygen). It can result in right-sided heart disease (cor pulmonale). Signs include difficulty breathing, cyanosis, and exercise intolerance.[49]
Jump up ^ Mazzaferro, Elisa M. (2006). “Emergency Approach to Toxins” (PDF). Proceedings of the North American Veterinary Conference. Archived from the original (PDF) on September 29, 2007. Retrieved February 13, 2007.
How to treat: Prevention is your best option. It starts with getting your dog shots every year. You should also monitor your dog’s activity to make sure he isn’t interacting with rabies infected animals in the wild. If you suspect that your dog has rabies, call Animal Control immediately and avoid your dog as much as possible.
Heat stroke can occur in dogs, especially in flat-faced breeds such as the Bulldog or in giant breeds. Breed, lack of water, exercise, and high ambient temperature predispose dogs to heat stroke. Signs include vomiting, diarrhea, collapse, difficulty breathing, and body temperature approaching 42 °C to 43 °C. Treatment includes cooling the dogs with wet towels and fans, intravenous fluid therapy, and other supportive care.[165] If a dog’s temperature begin to drop to around 40 °C, stop the cooling process. Once a dog’s body begins to cool, it can drop quickly and getting them too cool can create different problems. Allow the dog only a couple of laps of water until their temperature begins to drop to a more normal level. Do not allow a dog to gulp large quantities of water. If a dog is panting excessively and then drinks a lot of water, he will swallow large amounts of air with the water and this can cause an equally life-threatening case of gastric dilatation volvulus (bloat) in their stomach.[166]
Certain breeds are more likely to develop particular tumors, larger ones especially. The Golden Retriever is especially susceptible to lymphoma, with a lifetime risk of 1 in 8.[19] Boxers and Pugs are prone to multiple mast cell tumors.[18] Scottish Terriers have eighteen times the risk of mixed breed dogs to develop transitional cell carcinoma, a type of urinary bladder cancer.[20]
Diabetes mellitus in dogs is type 1, or insulin dependent diabetes: a lack of insulin production due to destruction of pancreatic beta cells.[85][86][87] Current research indicates no evidence of type 2 diabetes in dogs.[88] Among the causes of diabetes mellitus in dogs are autoimmune disease or severe pancreatitis.[89] Forms of diabetes which may not be permanent, depending on the amount of damage to the beta cells of the endocrine pancreas,[90] are transient and secondary diabetes. Some causes of transient or secondary diabetes are Cushing’s syndrome, glucocorticoid, progestin or other steroid use, and the hormones of pregnancy or heat. In these cases, correcting the primary medical issue may mean a return to non-diabetic status.[89][91][92] Common signs include weight loss, increased drinking and urination, and cataracts. Treatment involves insulin replacement therapy,[93] and use of a diet high in fiber and complex carbohydrates.[94] Oral diabetes medications cannot be used for dogs because none repair or surmount the permanent damage to the beta cells of the pancreas.[86][95][96][97]
Grapes and raisins can cause acute kidney failure in dogs [38] (see also grape and raisin toxicity in dogs). The exact mechanism is not known, nor is there any means to determine the susceptibility of an individual dog. While as little as one raisin can be toxic to a susceptible 10 pounds (4.5 kg) dog, some other dogs have eaten as much as a pound of grapes or raisins at a time without ill effects. The affected dog usually vomits a few hours after consumption and begins showing signs of renal failure three to five days later. A mycotoxin is suspected to be involved, but one has not been found in grapes or raisins ingested by affected dogs. The reason some dogs develop renal failure following ingestion of grapes and raisins is not known.[39][40][41][42] The most common pathological finding is proximal renal tubular necrosis.[43]
Sarcoptic mange is a parasitic skin disease that is caused by a tiny mite. Mange is transmitted between animals through close contact. In dogs, the mite causes severe itching and self-inflicted wounds from scratching.
Jump up ^ Morrow, C. M. K.; Valli, V. E.; Volmer, P. A.; Eubig, P. A. (2005). “Canine Renal Pathology Associated with Grape or Raisin Ingestion: 10 Cases”. J. Vet. Diagn. Investig. 17 (3): 223–31. doi:10.1177/104063870501700302. PMID 15945377.

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