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Genetics and environmental factors also play a role in cancer development. Some credit the uptick in canine cancer rates to dogs simply living longer with better health care options. Other blame dog “junk” food for the rise, with brand-name foods using ingredients thought to cause cancer. Check the labels and avoid BHT, BHA, and ethoxyquin.
Subvalvular aortic stenosis (Subaortic stenosis; SAS) is a congenital disease in dogs characterized by left ventricular outflow tract obstruction by a discrete ring or tunnel of fibrous tissue immediately below the aortic valve. It is inherited in Newfoundlands, and also found in Golden Retrievers, Rottweilers, Boxers, Bulldogs, German Shepherds, and Samoyeds. Signs include a left basilar systolic heart murmur, weak femoral pulse, fainting and exercise intolerance. Dogs with severe SAS are predisposed to dying suddenly.[49]
Aspergillosis* is a fungal disease that in dogs is caused primarily by Aspergillus fumigatus. Infection is usually in the nasal cavity. Typical signs in dogs include sneezing, nasal discharge, bleeding from the nose, and ulcerations of the nose.[23]
Demodicosis, also known as demodectic mange, is caused by Demodex canis mites which live in small numbers in sebaceous glands and hair follicles. These mites can cause inflammation and hair loss, and may also lead to secondary bacterial infections such as fever, lethargy, and enlarged lymph nodes.
There are some bacteria that are contagious from dog to dog. The most notable of these are Bordetella bronchiseptica, one of the causes of kennel cough, Leptospira sp, which cause leptospirosis,[3][4] and Brucella canis, cause of brucellosis in dogs. There are also common tick-borne bacterial diseases, including Lyme disease, ehrlichiosis, and Rocky Mountain spotted fever.
Jump up ^ Shearman, JR; Wilton, AN. (2007). “Elimination of neutrophil elastase and adaptor protein complex 3 subunit genes as the cause of trapped neutrophil syndrome in Border collies”. Animal Genetics. 38 (2): 188–189. doi:10.1111/j.1365-2052.2007.01565.x. PMID 17302793.
6. Rabies: Rabies is the disease made famous in the hearbreaking scene in Old Yeller. Thankfully, the widespread use of the rabies vaccine in recent years has made its occurrence in pets in the U.S. quite rare. However, it is still present in wild animal populations, and because rabies is always fatal, it’s critical to make sure that your pets are current on their rabies vaccination.
There has been some speculation that walking dogs in particular areas of the countryside may be a contributing factor, but the Forestry Commission has yet to warn of any specific sites being dangerous, reassuring dog owners by saying “Many thousands of dogs are walked in the countryside every day and it is important to remember that only a very small number of dogs have been affected.”
Leptospirosis is a zoonotic disease caused by bacteria of the genus Leptospira. Humans and dogs become infected through contact with water, food, or soil containing urine from infected animals. This may happen by swallowing contaminated food or water or through skin contact, especially with mucosal surfaces, such as the eyes or nose, or with broken skin. In dogs, transmission most commonly occurs by drinking puddle, pond, or ditch water contaminated by urine from infected wildlife such as squirrels or raccoons. The liver and kidney are most commonly damaged by leptospirosis. Vasculitis can occur, causing edema and potentially disseminated intravascular coagulation (DIC). Myocarditis, pericarditis, meningitis, and uveitis are also possible sequelae.[5]
Obesity is an increasingly common problem in dogs in Western countries. As with humans, obesity can cause numerous health problems in dogs (although dogs are much less susceptible to the common cardiac and arterial consequences of obesity than humans are). According to a study published in the Journal of Veterinary Internal Medicine, the prevalence of obesity in dogs is between 22 and 40 percent.[61]
Alabama dog rot was first identified amongst greyhounds in the state of Alabama in the 1980s. After this first flair up, the number of reported cases dwindled and as no clinical research was carried out, the disease was almost relegated to history. Because no one has been able to determine what causes the disease, it is now only recognisable by its collection of clinical symptoms.
Jump up ^ Meurs KM1, Lahmers S, Keene BW, White SN, Oyama MA, Mauceli E, Lindblad-Toh K. A splice site mutation in a gene encoding for PDK4, a mitochondrial protein, is associated with the development of dilated cardiomyopathy in the Doberman pinscher. Hum Genet. 2012 Aug;131(8):1319-25.
Macadamia nuts can cause non-fatal stiffness, tremors, hyperthermia, and abdominal pain.[48] The exact mechanism is not known. Most dogs recover with supportive care when the source of exposure is removed.
Leishmaniasis is a protozoan disease of people and animals. It is transmitted by sandflies and is uncommon in North America. The two forms of the disease are visceral and cutaneous. The cutaneous form of leishmaniasis is most common in people and appears as one or more painless ulcers on the skin. Visceral leishmaniasis is less common and is characterized by fever, weight loss, enlarged spleen, and anemia. Dogs can develop both forms at the same time and have a variety of symptoms.
Atrial septal defect* is a hole in the division between the heart atria (upper chambers of the heart). It is an uncommon abnormality in dogs. Most are not clinically significant, but large defects can cause right heart failure and exercise intolerance. Standard Poodles are the most common breed diagnosed with ASD in the USA.[49]
Ticks* are an external parasite of the dog and can spread diseases such as Lyme disease, Rocky Mountain spotted fever, babesiosis, and ehrlichiosis. They can also cause a neurological disorder known as tick paralysis.[32]
Histoplasmosis, caused by Histoplasma capsulatum, is a disease with a worldwide distribution. In the United States it is mainly found in the Mississippi and Ohio River areas, most commonly in bird and bat feces. Signs include weight loss, cough, fever, enlarged lymph nodes, and gastrointestinal symptoms.[11] Coccidioidomycosis, caused by Coccidioides immitis, is found in arid and semi-arid regions of Central and South America, Mexico, and southwestern United States. Signs include weight loss, fever, cough, enlarged lymph nodes, and lameness.[12][13]
Pulmonic stenosis* is a congenital heart disease in dogs characterized by right ventricular outflow tract obstruction. Most commonly the narrowing occurs at the pulmonary valve but it can also occur below the valve (subvalvular) or above the valve (supravalvular). The most commonly affected breeds include terriers, Bulldogs, Miniature Schnauzers, Chihuahuas, Samoyeds, Beagles, Keeshonds, Mastiffs, and Bullmastiffs. Signs may include exercise intolerance, but often there is only a heart murmur.[49]
Discoid lupus erythematosus is an uncommon autoimmune disease of the skin in dogs. It does not progress to systemic lupus erythematosus in dogs. The most common initial symptom is scaling and loss of pigment on the nose.[34]
Ever think, “I should Spin more,” and then remember how much you hate Spinning? Same for dogs. Not every dog is a runner or a swimmer or will want to play fetch. In fact, says Case, “If you haven’t started your dog swimming before the age of 1 or 2, it’s not going to like it”—even if it has webbed feet. “There are many more owners who want their dogs to swim than there are dogs that want to get in the water.” Tip: There’s no real data on the optimum cardio workout for dogs, says Kerns, “but the more you can get your dog outside—with the sun overhead and grass under its paws—the better.”
Echinococcosis is a parasitic disease caused by eating or drinking food and water contaminated with a specific type of tapeworm eggs or through contact with an infected animal. Dogs become infected by eating tissue of an infected animal. Dogs rarely show any signs of disease, but if they are infected with a large number of worms, dogs can have diarrhea and enteritis.
Ectropion (eyelid folding outward) is a common condition in dogs, usually affecting the lower lid. Breeds associated with ectropion include the Cocker Spaniel, the St. Bernard, the Bloodhound, and the Basset Hound.[62]
Valley Fever is the most serious and life-threatening of the group, mainly impacting hot, dry, dusty desert areas of California, Arizona, and Texas. The fungi are usually buried in the soil but can be displaced a number of ways—earthquakes, construction, rain—and released into the air where dogs can inhale it. If your dog develops respiratory symptoms, the disease can be deadly.
Antifreeze* is very dangerous to dogs and causes central nervous system depression and acute renal failure. Treatment needs to be within eight hours of ingestion to be successful.[168] See Ethylene glycol poisoning.

Prostate cancer* is rare in dogs and occurs in both intact and neutered animals. It is malignant. The most common type is adenocarcinoma. Signs include blood in the urine and straining to urinate or defecate. It most commonly spreads to bone and the lungs.[161]
Jump up ^ Ruchinsky, Renee; et al. (2010). “Diabetes Management Guidelines for Dogs and Cats-page 7” (PDF). American Animal Hospital Association (AAHA. Archived from the original (PDF) on 5 March 2012. Retrieved 25 January 2011.(PDF)
Antifreeze (ethylene glycol), due to its sweet taste, poses an extreme danger of poisoning to dogs and cats if ingested. Even a very small amount such as a tablespoon can easily prove fatal. The antifreeze itself is not toxic, but is metabolized via the liver to the toxins glycolate and oxalate, which cause intoxication and vomiting, metabolic acidosis, and finally acute kidney failure leading to seizures and death. By the time clinical signs are observed, the kidneys are usually too damaged for the dog to survive so acting quickly is important. Immediate treatments include inducing vomiting by using apomorphine or dilute hydrogen peroxide solution (if this can be done shortly after ingestion), but these merely reduce the amount absorbed – immediate veterinary treatment is still usually imperative due to the high toxicity of the compound. Medical treatments may include fomepizole (preferred treatment) which competes favorably with the toxin in the body, ethanol which competes favorably in the liver long enough to allow excretion to take place, activated charcoal to further reduce uptake of undigested product, and hemodialysis to remove toxins from the blood. Dogs should not be allowed access to any place in which an antifreeze leak or spill has happened until the spill is completely cleaned out. Some brands of antifreeze contain propylene glycol instead of ethylene glycol and are marketed as being less harmful or less attractive to animals.
Rocky Mountain spotted fever* is a rickettsial disease that occurs in dogs and humans. It is caused by Rickettsia rickettsii and spread by ticks of the genus Dermacentor. Signs are similar to human disease, including anorexia, fever, and thrombocytopenia.[12]
Pyometra is an infection of the uterus. It is a common and potentially fatal condition in dogs. The main risk period for a female is for eight weeks after her peak standing heat (or estrus cycle) has ended.[6]
Samoyed hereditary glomerulopathy (SHG) is an hereditary noninflammatory disease, of the renal glomeruli occurring in the Samoyed breed of dog. The disease has been shown to be a model for hereditary nephritis (HN) in humans[153]
Nutmeg is highly neurotoxic to dogs and causes seizures, tremors, and nervous system disorders which can be fatal. Nutmeg’s rich, spicy scent is attractive to dogs which can result in a dog ingesting a lethal amount of this spice. Eggnog and other food preparations which contain nutmeg should not be given to dogs.[45][46][47]
There are topical medicines to repel and kill ticks you put directly on your dog’s fur, like Frontline and K9 Advantix. There are also pills, like NexGard, and even collars your dog can wear, like Preventic. Just keep in mind the effectiveness of topical medicines decreases through the month, especially if your dog goes swimming or has a bath. Year-round prevention is best.

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