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Yes, puppies are a bundle of energy, but even they need disciplined exercise like leash walks. However, don’t start running and hiking with your pooch until your larger-breed dog is at least 1.5 years old. This will help avoid injuries while the growth plates in the legs and other long bones are still knitting closed. Tip: Be sure to build up your dog’s endurance, just as you did your own, if you’re hoping to take it with you on those marathon-training runs.
Jump up ^ Rijnberk A. (2002). “The mammary gland, an endocrine gland”. Nederlands tijdschrift voor geneeskunde. Nederlands Tijdschrift voor Geneeskunde (PubMed Summary in English). 146 (51): 2457–62. PMID 12534096.
Jump up ^ Thrusfield, M. V; Aitken, C. G. G; Muirhead, R. H (1989). “A field investigation of kennel cough: Efficacy of vaccination”. J. Small Animal Pract. 30 (10): 550. doi:10.1111/j.1748-5827.1989.tb01471.x.
Syringomyelia* is a condition where a fluid filled sac develops in the spinal cord. The most important cause in dogs is by a Chiari I malformation, which is when an underdeveloped occipital bone interferes with spinal fluid circulation and results in fluid accumulation in the cervical spinal cord. This is a congenital disease most commonly found in small breeds such as the Brussels Griffon and the Cavalier King Charles Spaniel. Other breeds known to be affected include the Bichon Frise, Boston terrier, bull terrier, Chihuahua, French bulldog, Havanese, King Charles spaniel (the English toy spaniel), Maltese, miniature dachshunds, miniature and toy poodles, Papillon, Pomeranian, Pugs, Shih Tzu, Staffordshire bull terrier, and the Yorkshire terrier. Signs may include ataxia, weakness, and neck pain.[55]
“Anytime you’re out with your dog,” says Pat Miller, author of The Power of Positive Dog Training, “one of you is training the other.” Better for it to be you. Begin as early as 8 weeks, before it picks up bad behaviors, and continue even into old age to keep your dog sharp. Make training about reward, not punishment. (Old-school devices like choke collars injure and instill fear, Miller says, “the most common cause of canine aggression.”) When housebreaking, “keep your puppy under close supervision and take it outside more often than he needs to go,” says Miller. “Reward it when it goes to the bathroom so it learns that this is the right way to do it.” Tip: “A well-trained dog has more opportunities to improve its physical health,” Miller adds. Walks, fetch, and agility training are more fun for you both if your dog will come when called, wait when asked, and greet other people and pups politely.
There are some bacteria that are contagious from dog to dog. The most notable of these are Bordetella bronchiseptica, one of the causes of kennel cough, Leptospira sp, which cause leptospirosis,[3][4] and Brucella canis, cause of brucellosis in dogs. There are also common tick-borne bacterial diseases, including Lyme disease, ehrlichiosis, and Rocky Mountain spotted fever.
Conjunctivitis* is inflammation of the conjunctiva. In dogs it is most commonly caused by mechanical irritation (such as by entropion, ectropion, or trichiasis), allergies, and keratoconjunctivitis sicca. Any bacterial infection is usually secondary.[70]
Rabies is a viral disease that may affect the brain and spinal cord of all mammals, including cats, dogs and humans. This preventable disease has been reported in every state except Hawaii. There’s good reason that the very word “rabies” evokes fear in people—once symptoms appear, rabies is close to 100% fatal.
Blastomycosis is another very serious fungal disease that affects dogs near the Great Lakes region and other Eastern U.S. river basins. The fungus lives in soil sheltered from the sun, mainly along riverbanks, lakes, and swamps. Most dogs who get it live within 400 meters of a body of water. Large breed male dogs are most at risk and symptoms typically include difficulty breathing, skin lesions, and loss of appetite.
Jump up ^ Mazzaferro, Elisa M. (2006). “Emergency Approach to Toxins” (PDF). Proceedings of the North American Veterinary Conference. Archived from the original (PDF) on September 29, 2007. Retrieved February 13, 2007.

There are all types of canine cancers, and they seem to be on the rise. A staggering 50 percent of dogs aged ten and older will develop some form of cancer, and it’s the leading cause of death of dogs in this age group.
You need a heads-up on potential health problems and their risk factors, so you can prevent them altogether. Well, here it is: the most common yet preventable dog diseases, along with expert advice from California veterinarian Dr. Nicole Eckholm of the Pet Emergency and Specialty Center of Marin.
Diabetes mellitus in dogs is type 1, or insulin dependent diabetes: a lack of insulin production due to destruction of pancreatic beta cells.[85][86][87] Current research indicates no evidence of type 2 diabetes in dogs.[88] Among the causes of diabetes mellitus in dogs are autoimmune disease or severe pancreatitis.[89] Forms of diabetes which may not be permanent, depending on the amount of damage to the beta cells of the endocrine pancreas,[90] are transient and secondary diabetes. Some causes of transient or secondary diabetes are Cushing’s syndrome, glucocorticoid, progestin or other steroid use, and the hormones of pregnancy or heat. In these cases, correcting the primary medical issue may mean a return to non-diabetic status.[89][91][92] Common signs include weight loss, increased drinking and urination, and cataracts. Treatment involves insulin replacement therapy,[93] and use of a diet high in fiber and complex carbohydrates.[94] Oral diabetes medications cannot be used for dogs because none repair or surmount the permanent damage to the beta cells of the pancreas.[86][95][96][97]
Pulmonary hypertension* is high pressure in the pulmonary artery. In dogs it can be caused by heartworm disease, pulmonary thromboembolism, or chronic hypoxemia (low oxygen). It can result in right-sided heart disease (cor pulmonale). Signs include difficulty breathing, cyanosis, and exercise intolerance.[49]
Because diarrhea can easily lead to dehydration, be sure your dog has plenty of clean water available, then take your pooch to the vet if the diarrhea persists for more than a day, or immediately if there’s also fever, lethargy, vomiting, dark or bloody stools, or loss of appetite.
Liver failure* is common. Signs include vomiting, loss of appetite, weight loss, and jaundice. Causes include bacterial or viral infection, toxic insult, cancer, copper storage diseases, or it may be idiopathic.[175]
Female cats and dogs are seven times more likely to develop mammary tumors if they are not spayed before their first heat cycle.[73] The high dietary estrogen content of the average commercial pet food may be contributing factors in the development of mammary cancer, especially when these exogenous sources are added to those normal estrogens produced by the body. Dog food containing soybeans or soybean fractions have been found to contain phytoestrogens in levels that could have biological effects when ingested longterm.[74]
Jump up ^ Shearman, JR; Wilton, AN. (2007). “Elimination of neutrophil elastase and adaptor protein complex 3 subunit genes as the cause of trapped neutrophil syndrome in Border collies”. Animal Genetics. 38 (2): 188–189. doi:10.1111/j.1365-2052.2007.01565.x. PMID 17302793.
Vaccine reactions are adverse events which occur following vaccination, including granuloma formation, but most commonly the term vaccine reaction is used to describe a type I hypersensitivity reaction. The most common signs are facial swelling and hives, but more rarely very serious signs such as hypotension and collapse may occur.[180]
Jump up ^ . Certain preparation methods of chocolate with other food items may increase the resultant theobromine levels. Such common prepared items include chocolate-coated accessory-fruits such as strawberries and combinations including caster sugars such as chocolate cookies. Carson, Delbert G.; Griffin, James M. (1992). Dog Owner’s Home Veteniary Handbook,. MacMillan General Reference. p. 19. ISBN 0-87605-537-4.
Luxating patella is a medial or lateral displacement of the patella, or kneecap. It is strongly suspected to be inherited, but can also result from trauma.[36] It is more common in smaller breeds of dogs [1]
Fleas and ticks of various species can be acquired and brought home by a dog, where they can multiply and attack humans (and vice versa). These two parasites are particularly important to note, now that tick-borne Lyme Disease has become endemic throughout a large area, in addition to other similar diseases such as Rocky Mountain Spotted Fever. Although dogs do not seem to be as susceptible to such diseases as humans, similar rickettsial diseases have been spread by dogs to humans through such mechanisms as a dog killing an infected rabbit, then shaking itself off in the house near enough to its owners to fatally infect most of the family.
Cocoa within chocolate contains theobromine,[34] a chemical stimulant that, together with caffeine and theophylline, belongs to the group of methylxanthine alkaloids. Dogs are unable to metabolize theobromine effectively. If they eat chocolate, the theobromine can remain in their bloodstreams for days, and dogs may experience fast heart rate, severe diarrhea, epileptic seizures, heart attacks, internal bleeding, and eventually death.[35] “One ounce of milk chocolate per pound of body weight is a potentially lethal dose in dogs.”[36] In case of accidental intake of chocolate by especially a smaller dog, contact a veterinarian or animal poison control immediately; it is commonly recommended to induce vomiting within two hours of ingestion. If chocolate ingestion is suspected (mostly dark or baking chocolate), hydrogen peroxide can be used to safely induce vomiting, then making a trip to the veterinarian is suggested. Large breeds are less susceptible to chocolate poisoning, but can still die after eating four ounces[37] of chocolate.
Puppies in breeding facilities or shelters are most at risk of coming in contact with an infected dog. Most dogs contract parvo by coming into contact with the poop of a contaminated dog, either directly or indirectly, like on a shoe.
Melanomas* account for four to six percent of skin tumors in dogs and are usually benign. They are the second most common tumor of the toe and are malignant in this location. Malignant melanoma is also a common oral tumor in dogs. Malignant tumors most commonly spread to the lymph nodes and lungs.[161]
Most diseases that affect dogs or humans are not transferable between the two species. Diseases that can be transmitted from animals to humans are terrmed zoonoses. A well-known zoonosis is rabies, a viral infection transmitted through a bite. A common bacterial zoonosis is leptospirosis, transmitted through urine. Some of the most important zoonoses are parasitic. Zoonotic intestinal parasites transmitted through contact with feces include Toxocara canis (the canine roundworm), which causes toxocariasis, visceral larva migrans, and ocular larva migrans, and hookworms, which can cause cutaneous larva migrans. Zoonotic skin parasites include scabies, caused by the mite Sarcoptes scabiei. The most common zoonotic fungal disease is ringworm, caused in this case by Microsporum canis.
“Be aware of it and insist a blasto test be done early,” Picken says. “It’s a small price to pay to eliminate the possibility of a tragic outcome. I found the perfect rescue dog and was ecstatic about the thought of having so many good years with him. To go from that to the heartbreak of losing him so quickly is a pretty steep fall.”
Overdoses of vitamins can be harmful in dogs. As an example, calcium in excess can cause bone problems, especially in the large-breed dogs. Over-supplementation of vitamins A and D can cause vitamin toxicity in dogs.[68] Excess vitamin A can cause dehydration, joint pain and can also harm the blood vessels, while too much vitamin D can cause muscular atrophy, or loss of appetite.
Developmental orthopedic diseases include panosteitis and hypertrophic osteodystrophy. Panosteitis occurs in large and giant breed dogs usually between the age of five and fourteen months and manifests as fever, pain, and shifting leg lameness. Hypertrophic osteodystrophy is also seen in young large and giant breed dogs and is characterized by pain, lameness, fever, and swelling of the long bone metaphysis.
Rabies (hydrophobia) is a fatal viral disease that can affect any mammal, although the close relationship of dogs with humans makes canine rabies a zoonotic concern. Vaccination of dogs for rabies is commonly required by law. Please see the article dog health for information on this disease in dogs.[1]
How to treat: Sadly, arthritis cannot be cured, but there are things you can do to make it easier on your pet as he ages. Diet and nutrition are the two biggest things you can do to slow down the aging (and arthritis) process. Regular walks and a balanced diet of proper (age appropriate) food will keep your dog’s nutrition levels where they should be. Look for food labeled “Senior” and pay attention not to over or under feed. If your dog’s arthritis is severe, your vet can prescribe medications to alleviate the symptoms.
Every diabetic dog is an individual and will respond differently to therapy. Diabetes treatment is based on how severe the signs of disease are and whether there are any other health issues that could complicate therapy.
“If you think your dog is too skinny, it’s probably the right weight,” Case say. Dogs with excess weight are more prone to joint problems and diabetes, among other health issues (sounds familiar). How to tell if Fluffy is chubby? “It’s all about the feel,” she adds. “Ribs shouldn’t be visible, but easily felt.” Tip: Rub your hands up and down your dog’s flank. You should feel the ridges of its ribs without having to push in to find them.
Lick granuloma also known as acral lick dermatitis, is a skin disorder in dogs resulting from an urge to lick the lower portion of the leg. The lesion from the incessant licking is a thickened, firm, oval plaque.[34]
Tick-borne diseases are common in dogs. Lyme disease, or borreliosis, is caused by Borrelia burgdorferi and spread by Ixodes pacificus on the West coast of the United States and by I. scapularis (deer tick) in the rest of the U.S. Signs and symptoms include fever, joint swelling and pain, lameness, and swelling of the lymph nodes. It has been diagnosed in dogs in all 48 states of the continental U.S.[7] Ehrlichia canis, which causes canine ehrlichiosis, and Rickettsia rickettsii, which causes Rocky Mountain spotted fever, are both spread by the American dog tick, Dermacentor variabilis, and the brown dog tick, Rhipicephalus sanguineous.[8]
Umbilical hernia* is a failure of the umbilical ring of the abdominal wall to close. They are very common and can be caused by genetics or by traction on the umbilical cord or by the cord being cut too close to the body. They are corrected by surgery.[160]
Some dog owners opt for no treatment of the cancer, in which case palliative end of life care, including pain relief, should be considered. Regardless of how you proceed after a diagnosis of cancer in your pet, it is very important to consider his quality of life when making future decisions.
Signs of vestibular disease include head tilt, circling, nystagmus (an abnormal movement of the eyes), and difficulty or inability to stand. These clinical signs are similar to those seen in humans experiencing vertigo. Vestibular disease may have many causes. Elderly dogs are susceptible to an idiopathic (meaning due to unknown causes) form of vestibular disease commonly called “old dog vestibular disease” or idiopathic peripheral vestibular disease. The signs may improve rapidly or take a few days. Less commonly, vestibular signs can also be caused by inner ear disease, a brain tumor, a stroke, or other causes. The major risk with idiopathic peripheral vestibular disease is that the dog is often unable to eat, drink, or go outside to urinate or defecate. These cases must receive supportive therapy of intravenous fluids and nutrition; a light sedative is sometimes administered, as the dog may be very stressed by the experience.
The first sign of Alabama Rot is skin sores that have not been caused by a physical injury. These sores can present as lesions, swelling, a patch of red skin, or may be open and ulcer-like. The sores are most commonly found below the knee or elbow or occasionally on the stomach or face. Usually, this will cause localised hair loss and the dog will begin licking the wound. These lesions will be followed – between two and seven days later – with outward symptoms of kidney failure: reduced appetite, fatigue, and vomiting. 
Complications include dehydration, secondary infections, sepsis and a condition in which part of the intestine slips into the part below it (called intussusception). CPV also can damage the spleen. Dogs that have another health condition are at increased risk for developing severe complications and illness.

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