immune disease in dogs |

10. Kidney disease: Kidney disease is common in senior cats, but also seen in cats and dogs of all ages. It can be congenital or develop as the pet ages. While cats with kidney disease can be treated and kept healthy for several years in most cases, dogs typically deteriorate more quickly. Kidney health is typically evaluated with annual bloodwork at your veterinarian.
Lead poisoning* is uncommon in dogs. Exposure to lead is from eating paint chips from lead-based paint (found in houses painted prior to 1950), and eating lead objects such as shot, fishing sinkers, or counterweights. Signs of poisoning include vomiting, diarrhea, blindness, seizures, and tremors.[168]
Facial nerve paralysis* is most commonly caused in dogs by trauma, otitis media, or as an idiopathic condition. Signs include an inability to blink, drooping of the ear, and drooping of the lips on the affected side, although in chronic conditions fibrosis occurs and the ear and lips may appear to be in an abnormal position.[60]
How to treat: First, determine what the allergen is. Common allergies can be treated by changing your dog’s food or the shampoo you use when bathing. Seasonal or environmental allergies can be treated with medications, but those will eventually weaken the immune system if administered repeatedly.

Poisoning with pain medications is common. Aspirin, paracetamol (acetaminophen, Tylenol), ibuprofen (Advil), and naproxen (Aleve) can all cause severe clinical signs in dogs, including vomiting blood, diarrhea, and abdominal pain.[57][58][59][60] Specifically, aspirin can cause metabolic acidosis and bleeding disorders, acetaminophen can cause liver disease, ibuprofen can cause kidney disease, and naproxen can cause ulcers in the stomach, which can perforate. Treatment depends on the clinical signs.
Contact your veterinarian immediately if your dog shows any of the clinical signs mentioned on the list above. Should your dog receive a diagnosis of cancer, you may wish to consult a veterinary oncologist, often employed by specialty veterinary practices and teaching hospitals.
There has been some speculation that walking dogs in particular areas of the countryside may be a contributing factor, but the Forestry Commission has yet to warn of any specific sites being dangerous, reassuring dog owners by saying “Many thousands of dogs are walked in the countryside every day and it is important to remember that only a very small number of dogs have been affected.”
Jump up ^ Braddock JA, Church DB, Robertson ID (2004). “Selegiline Treatment of Canine Pituitary-Dependent Hyperadrenocorticism” (PDF). Australian Veterinary Journal. Archived from the original (PDF) on 29 November 2010. Retrieved 8 April 2011. (PDF)
Renal failure (kidney failure) * is common in dogs and may be found in acute or chronic forms. It is defined by a loss of function of about 75 percent of the filtration system of the kidney and characterized by azotemia and low specific gravity of the urine.[148] Acute renal failure can be caused by loss of blood supply, hypercalcemia, or toxins such as ethylene glycol (antifreeze) or aminoglycoside antibiotics[149] (see: ethylene glycol poisoning). Chronic renal failure can be congenital and/or inherited or caused by cancer, infection, hypertension, glomerulonephritis, amyloidosis, progressive interstitial fibrosis, or any of the causes of acute renal failure.[150]
Most people who become sick with campylobacteriosis will have diarrhea, cramping, abdominal pain, and fever within 2-5 days after exposure to the organism. Campylobacter can cause serious life-threatening infections in infants, older persons, and those with weakened immune systems.
Female cats and dogs are seven times more likely to develop mammary tumors if they are not spayed before their first heat cycle.[73] The high dietary estrogen content of the average commercial pet food may be contributing factors in the development of mammary cancer, especially when these exogenous sources are added to those normal estrogens produced by the body. Dog food containing soybeans or soybean fractions have been found to contain phytoestrogens in levels that could have biological effects when ingested longterm.[74]
Nutritious mass-market food abounds, says Linda Case, author of Dog Food Logic, but some of the best products come from smaller companies that make food in their own US facilities. Sure, you can feed your dog on 15 cents a day, but making the investment in higher-priced food, say at a few dollars a day, can mean the difference between giving your dog chicken and serving it ground chicken heads (yes, gross!). Tip: Grain should not be one of the first two ingredients on the label, and the protein source should be named (“trout” not “fish,” for example). Bonus: Worried about pet-food recalls? Follow the American Veterinary Medical Association on Twitter @AVMARecallWatch or its Facebook page to stay informed.
Epilepsy in dogs can be a primary, idiopathic, inherited disorder or secondary to previous head trauma or CNS infections. Idiopathic epilepsy is commonly found in breeds such as German Shepherd Dogs, Beagles, and Dachshunds. The most common sign recurring generalized seizures beginning at a young adult age.[56]
Skin diseases are very common in dogs. Atopy, a chronic allergic condition, is thought to affect up to 10 percent of dogs.[16] Other skin diseases related to allergies include hot spots and pyoderma, both characterized by secondary bacterial infections, food allergy, ear infections, and flea allergy dermatitis. Canine follicular dysplasia is an inherited disorder of the hair follicles resulting in alopecia (baldness). Mange is an infectious skin disease caused by mites. Endocrine diseases such as hypothyroidism and Cushing’s syndrome can also manifest as skin problems like alopecia or recurring bacterial infections. Another class of integumentary malady is hygromas, a swelling typically on or near the elbow joint. Nutrition may also play a role in skin disease, as deficiencies in certain nutrients may result in scaling, redness, oiling, balding, and/or itching of the skin.[17](See dog skin disorders for specific nutrients that impacts skin)
“He is soooo cute,” you thought when you first laid eyes on your dog. And—yay!—he seemed to like you too. So you brought him home—only to realize that maybe you weren’t totally prepared for the work this relationship involved. Well, your mom was right (again): Owning a dog IS a big responsibility, from training to feeding to keeping it stress-free. “We don’t have that many years with our dogs,” says Whole Dog Journal editor Nancy Kerns. Here’s how to make sure each day is filled with health—and happiness for you both.
So keep those chompers clean! Brush regularly throughout your dog’s lifetime—meaning at least once a week—offer bully sticks or other hard chew toys to remove plaque, or get a professional teeth cleaning done at your vet’s office, which requires anesthesia but is quite effective.
If your veterinarian has diagnosed your dog with ringworm, he or she will explain what you must do to prevent the fungus from spreading to your other pets—and to the human members of the household. But keep in mind that if you have other pets, it’s likely that most of them have been exposed as well. Your veterinarian may recommend that you do the following:
Dental disease is one of the most common diseases in dogs. Accumulation of plaque and subsequently tartar leads to gingivitis and then periodontitis (gum disease). Periodontitis leads to loss of the bony attachment of the teeth and tooth loss. Preventive measures include tooth brushing, providing an appropriate diet (avoiding tinned and other soft foods and providing dental chew treats) and dental scaling and polishing. Cavities are uncommon in dogs.
“The concern among vets in the UK is that, unlike the Alabama Rot that affected greyhounds in America, the disease in the UK does not seem to target any specific breed, age, sex or weight of dog,” said Dr Huw Stacey, director of clinical services at Vets4Pets.
A dog who is up to date with his vaccinations and who has been bitten by a possibly rabid animal should also be given a rabies booster vaccine immediately and kept under observation (length will vary depending on your state laws).
Some dogs have food allergies just as humans do; this is particular to the individual dog and not characteristic of the species as a whole. An example is a dog becoming physically ill from salmon; many humans likewise have seafood allergies.
Jump up ^ Paciello, O.; Lamagna, F.; Lamagna, B.; Papparella, S. (2003). “Ehlers-Danlos–Like Syndrome in 2 Dogs: Clinical, Histologic, and Ultrastructural Findings” (PDF). Veterinary Clinical Pathology. 32 (1): 13–18. doi:10.1111/j.1939-165X.2003.tb00306.x. PMID 12655483. Retrieved 2007-01-01.
Pica in dogs may be a sign of Immune-mediated hemolytic anemia, especially when it involves eating substances such as tile grout, concrete dust, and sand. Dogs exhibiting this form of pica should be tested for anemia with a Complete blood count including Hematocrit levels, or Packed cell volume.[46][47]
Due to the indiscriminate nature of a dog’s appetite, gastrointestinal upset is a frequent occurrence in dogs. The most common symptoms are anorexia, vomiting, and diarrhea. Foreign body ingestion can lead to acute obstruction of the gastrointestinal tract, a very dangerous condition. Acute pancreatitis can also result from dietary indiscretion.
Bacterial diseases in dogs are usually not contagious from dog to dog; instead they are usually the result of wound colonization, opportunistic infections secondary to decreased resistance (often the result of viral infections), or secondary to other conditions (pyoderma secondary to skin allergies or pyometra secondary to cystic endometrial hyperplasia). These examples are not considered infectious diseases because they do not satisfy Koch’s postulates – for example Staphylococcus intermedius, a commonly isolated bacteria from skin infections in dogs, would not cause pyoderma when introduced to a healthy dog. In all likelihood that type of bacteria is already present on the skin of a healthy dog.
Jump up ^ Arnold S (1997). “[Urinary incontinence in castrated bitches. Part 1: Significance, clinical aspects and etiopathogenesis]”. Schweiz. Arch. Tierheilkd. (in German). 139 (6): 271–6. PMID 9411733.
Jump up ^ Davidson, Gigi (2000). “Providing Care for Veterinary Diabetic Patients-Canine Diabetes” (PDF). International Journal of Pharmaceutical Compounding. Archived from the original (PDF) on 29 March 2016. Retrieved 25 January 2011. (PDF)
Pericardial effusion* is a collection of fluid in the pericardium. It is usually serosanguinous (bloody fluid). Serosanguinous accumulation can be caused by cancer, usually hemangiosarcoma or a heart base tumor, idiopathic pericarditis. Rare causes include trauma, clotting disorders, and left atrial rupture. Serous accumulation is rare and caused by heart failure, peritoneopericardial diaphragmatic hernias, uremia, pericardial cysts, or hypoalbuminemia. Rarely pericardial effusion can be caused by infection and consist of pus. An echocardiogram should be done prior to draining the fluid, if possible, to identify the cause (e.g., tumor). Drainage of the fluid (pericardiocentesis) relieves the clinical signs and, in the case of idiopathic pericarditis, can be curative.[49]
About 4.5 million Americans receive dog bites each year, many of which require immediate medical attention. Young children 5 to 9 years old are most likely to bitten by dogs, with boys being bitten more often than girls.
Ocular tumors* in dogs are found in the eyelid, conjunctiva, third eyelid, cornea, sclera, iris, ciliary body, retina, choroid, optic nerve, and orbit. The most common types are Meibomian gland adenoma (eyelid), papilloma (eyelid), melanoma (eyelid, conjunctiva, sclera, iris, ciliary body, choroid), squamous cell carcinoma (conjunctiva), adenoma (ciliary body), adenocarcinoma (ciliary body), lymphoma (retina, choroid, ciliary body), medulloepithelioma (retina, choroid), ganglioglioma (retina, choroid), osteosarcoma (orbit), mast cell tumor (orbit), and optic nerve sheath meningioma.[161]

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