what causes cushing’s disease in dogs |

Granulomatous meningoencephalitis (GME) (including Pug Dog encephalitis and other noninfectious causes of meningoencephalitis) is an inflammatory disease of the central nervous system of dogs. It is a form of meningoencephalitis. The disease is more common in female toy dogs of young and middle age.
Canine glaucoma is an increase of pressure within the eye. It is a common condition in dogs. It can be caused by abnormal development of the drainage angle of the eye, lens luxation, uveitis, or cancer. Cocker Spaniels, Poodles, and Basset Hounds are predisposed.[69]
One of the most common fungal diseases in dogs is ringworm, or dermatophytosis, an infection of the skin, hair, or nails. There are three fungal species that cause ringworm in dogs. About 70 percent of infections are caused by Microsporum canis, 20 percent by M. gypseum, and 10 percent by Trichophyton mentagrophytes. Signs include hair loss and scaling of the skin. Treatment for localized ringworm is not always necessary as the disease is self-limiting, but the cliinical course can be shortened by using topical miconazole or clotrimazole. Generalized infections, most commonly seen in immunocompromised dogs, can be treated with oral antifungal drugs such as griseofulvin or itraconazole. Infection can spread to humans.[9]
Genetic conditions are a problem in some dogs, particularly purebreeds. For this reason many of the national kennel clubs require that dogs with certain genetic illnesses or who are deemed to be carriers cannot be registered. Some of the most common conditions include hip dysplasia, seen in large breed dogs, von Willebrand disease, a disease that affects platelets that is inherited in Doberman Pinschers, entropion, a curling in of the eyelid seen in Shar Peis and many other breeds, progressive retinal atrophy, inherited in many breeds, deafness, and epilepsy, known to be inherited in Belgian Shepherd Dogs, German Shepherd Dogs, Cocker Spaniels, and St. Bernards.[14]
Chocolate poisoning symptoms can last up to 72 hours. PetMD offers this chocolate toxicity meter to gauge your dog’s level of poisoning, but it’s still best to see a vet right away. For a true life story, read our post, My Dog Ate Chocolate. Here’s What Happened Next.
Subvalvular aortic stenosis (Subaortic stenosis; SAS) is a congenital disease in dogs characterized by left ventricular outflow tract obstruction by a discrete ring or tunnel of fibrous tissue immediately below the aortic valve. It is inherited in Newfoundlands, and also found in Golden Retrievers, Rottweilers, Boxers, Bulldogs, German Shepherds, and Samoyeds. Signs include a left basilar systolic heart murmur, weak femoral pulse, fainting and exercise intolerance. Dogs with severe SAS are predisposed to dying suddenly.[49]
Uveitis* is inflammation within the eye. Anterior uveitis (inflammation of the iris and ciliary body) is most common in dogs. The disease is usually immune-mediated in dogs, but may also be caused by trauma, cataracts, infectious canine hepatitis, leptospirosis, ehrlichiosis, or systemic fungal infections.[73]
If your dog will be housed outside, provide shelter such as a doghouse for when it is cold or rainy and shade for when it is hot. Protecting your dog from the changes in weather will reduce stress and help keep it healthy.
There are topical medicines to repel and kill ticks you put directly on your dog’s fur, like Frontline and K9 Advantix. There are also pills, like NexGard, and even collars your dog can wear, like Preventic. Just keep in mind the effectiveness of topical medicines decreases through the month, especially if your dog goes swimming or has a bath. Year-round prevention is best.
Depending on the size of your pup, some health problems are more prevalent than others. For instance, big dogs tend to deal with more bone and joint problems, whereas smaller dogs tend to suffer more with organ and breathing disorders. Again, each breed is unique, but it is important to understand what common dog illnesses and health issues affect your pet. See below for the most common types of dog health issues and make sure to take immediate action if you think something serious is wrong with your dog.
Lick granuloma also known as acral lick dermatitis, is a skin disorder in dogs resulting from an urge to lick the lower portion of the leg. The lesion from the incessant licking is a thickened, firm, oval plaque.[34]
Eye diseases are common in dogs. Cataracts, canine glaucoma, and entropion are seen in dogs. Canine-specific eye diseases include progressive retinal atrophy, Collie eye anomaly, sudden acquired retinal degeneration, and cherry eye. Injury to the eye can result in corneal ulcers.

Malignant histiocytosis (histiocytic sarcoma) is an aggressive cancer found primarily in certain breeds including the Bernese Mountain Dog, rottweiler, golden retriever and flat coated retriever. It is characterized by infiltration of the joints, lungs, spleen, lymph nodes, and other organs by malignant histiocytes.[6]
People who become infected with leptospirosis might not have any signs of the disease. Others will have nonspecific flu-like signs within 2-7 days after exposure. These symptoms usually resolve without medical treatment, but can reappear and lead to more severe disease.
Scotty Cramp is a disease in Scottish Terriers causing spasms and hyperflexion and hyperextension of the legs. It is caused by a disorder in serotonin metabolism that causes a deficiency of available serotonin.[6]
Because diarrhea can easily lead to dehydration, be sure your dog has plenty of clean water available, then take your pooch to the vet if the diarrhea persists for more than a day, or immediately if there’s also fever, lethargy, vomiting, dark or bloody stools, or loss of appetite.
Chocolate is a common cause of poisoning in dogs. The toxic principles in chocolate are theobromine and caffeine. Baker’s chocolate is the most dangerous form since it contains higher concentrations of these drugs, followed by semi-sweet, dark, and then milk chocolate. Signs include vomiting, diarrhea, tremors, difficulty walking, seizures, and heart problems.[171]
Blastomycosis* is a fungal disease caused by Blastomyces dermatitidis that affects both dogs and humans. Dogs are ten times more likely to be infected than humans. The disease in dogs can affect the eyes, brain, lungs, skin, or bones.[15]
Jump up ^ Rijnberk A. (2002). “The mammary gland, an endocrine gland”. Nederlands tijdschrift voor geneeskunde. Nederlands Tijdschrift voor Geneeskunde (PubMed Summary in English). 146 (51): 2457–62. PMID 12534096.
Hemolytic anemia* is a type of regenerative anemia found in dogs characterized by destruction of the red blood cell. The most important type is immune-mediated hemolytic anemia, which can be a primary disease or secondary to cancer, infection, drugs, or vaccinations. Antibodies are present on the cell surface, leading to lysis and severe anemia. Other causes of hemolytic lesion include hypophosphatemia, exposure to toxins such as lead, infections such as ehrlichiosis or babesiosis, and rarely, neonatal isoerythrolysis.[45] The behavioral condition pica, especially when involving the eating of concrete dust, tile grout, or sand, may be a sign of hemolytic anemia, indicating the need for a complete blood count to investigate a possible diagnosis.[46][47]
Nuclear sclerosis is a consistent finding in dogs greater than seven years old. Nuclear sclerosis appears as a bilateral bluish-grey haziness at the nucleus, or center of the lens,[62] and has little effect on vision.[66] This is may be confused with cataracts.[67]
Jump up ^ Grooters, Amy M. (2003). “Pythiosis, lagenidiosis, and zygomycosis in small animals”. The Veterinary Clinics of North America. 33 (4): 695–720. doi:10.1016/S0195-5616(03)00034-2. PMID 12910739.
Legg-Calvé-Perthes syndrome, also known as Perthes disease or avascular necrosis of the femoral head, is characterized by a deformity of the head of the femur and hip pain. It occurs in small breed puppies.[6]
Lyme disease* is a disease caused by Borrelia burgdorferi, a spirochaete, and spread by ticks of the genus Ixodes. Symptoms in dogs include acute arthritis, anorexia and lethargy. There is no rash as is typically seen in humans.[11]

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