Jump up ^ Dunayer EK, Gwaltney-Brant SM (October 2006). “Acute hepatic failure and coagulopathy associated with xylitol ingestion in eight dogs”. J. Am. Vet. Med. Assoc. 229 (7): 1113–7. doi:10.2460/javma.229.7.1113. PMID 17014359.
Cerebellar abiotrophy is caused by the death of Purkinje cells in the cerebellum. It results in progressive ataxia beginning at a young age. It is most commonly seen in Kerry Blue Terriers and Gordon Setters.
Retinal detachment* is caused in dogs by genetic disorders such as retinal dysplasia or Collie eye anomaly, trauma, inflammation or cancer. Reattachment may occur spontaneously or with medical or surgical therapy.
Some diseases and other health problems are common to both humans and dogs; others are unique to dogs and other animals. Dogs are susceptible to various diseases; similarly to humans, they can have diabetes, epilepsy, cancer, or arthritis.
Primary ciliary dyskinesia* is a dysfunction of cilia, which manifests as sperm immotility and respiratory disease. Signs include nasal discharge, recurring pneumonia, and infertility. Symptoms develop soon after birth.
Dilated cardiomyopathy (DCM) is a disease of heart muscle resulting in decreased myocardial contractility. The left ventricle compensates for this disease by growing larger (eccentric or volume overload hypertrophy; AKA dilation). The left atrial is also dilated when the disease is severe. It is seen in large/giant dog breeds such as Boxers, Great Danes, and Doberman Pinschers. It is usually idiopathic, but can also be caused by taurine deficiency in American Cocker Spaniels or doxorubicin use. A mutation in the gene that encodes for pyruvate dehydrogenase kinase 4 is associated with DCM in Doberman Pinschers in the USA. Dilated cardiomyopathy usually ultimately results in congestive heart failure. Atrial fibrillation is common in giant breed dogs with DCM. Doberman Pinschers more commonly have ventricular arrhythmias (e.g., premature ventricular complexes; ventricular tachycardia) that predispose them to sudden death (i.e., ventricular fibrillation).
Pemphigus is an uncommon autoimmune skin disease. The most common form in dogs is pemphigus foliaceus, which manifests as erosions and crusting of the skin and mucocutaneous junctions. Pemphigus vulgaris is more rare and manifests as blister-like lesions in the mouth and at mucocutaneous junctions. Bullous pemphigoid is most commonly seen in Dobermanns and Collies and appears as a scald-like lesion of the groin.
Jump up ^ Catchpole B, Ristic JM, Fleeman LM, Davison LJ (2005). “Canine diabetes mellitus: can old dogs teach us new tricks?”. Diabetologia. Diabetologica. 48 (10): 1948–56. doi:10.1007/s00125-005-1921-1. PMID 16151773.
Grapes and raisins can cause acute kidney failure in dogs  (see also grape and raisin toxicity in dogs). The exact mechanism is not known, nor is there any means to determine the susceptibility of an individual dog. While as little as one raisin can be toxic to a susceptible 10 pounds (4.5 kg) dog, some other dogs have eaten as much as a pound of grapes or raisins at a time without ill effects. The affected dog usually vomits a few hours after consumption and begins showing signs of renal failure three to five days later. A mycotoxin is suspected to be involved, but one has not been found in grapes or raisins ingested by affected dogs. The reason some dogs develop renal failure following ingestion of grapes and raisins is not known. The most common pathological finding is proximal renal tubular necrosis.
It is not yet clear whether or not vitamins and supplements should be administered in dogs—opinions among veterinarians vary widely. While some think that vitamins and supplements are necessary and can improve the health of a dog, others believe that they are unnecessary and may harm the dog. According to the U.S. Food and Drug Administration (FDA), dogs receive a complete and balanced diet from the commercially processed dog food alone. Pet owners who give their dogs homemade diets may incorporate extra vitamins and supplements.
Other diseases affecting dogs include endocrine diseases, immune-mediated diseases, and reproductive diseases. Diabetes mellitus, Cushing’s syndrome, Addison’s disease, and hypothyroidism are the most common endocrine diseases. Immune-mediated hemolytic anemia is a devastating disease that causes severe anemia in dogs through destruction by the immune system. It has been associated with vaccinations and certain drugs, although many cases are idiopathic. A similar but less severe immune disease is immune-mediated thrombocytopenia, characterized by destruction of platelets by the immune system. Clinical signs include bruising and petechiae (pinpoint bruising, often seen in the mouth). Common reproductive diseases include pyometra (distension of the uterus with pus), mammary tumors, and benign prostatic hyperplasia.
Eye diseases are common in dogs. Cataracts, canine glaucoma, and entropion are seen in dogs. Canine-specific eye diseases include progressive retinal atrophy, Collie eye anomaly, sudden acquired retinal degeneration, and cherry eye. Injury to the eye can result in corneal ulcers.
Craniomandibular osteopathy is a hereditary disease in West Highland White Terriers and also occurs in other terrier breeds. It is a developmental disease in puppies causing extensive bony changes in the mandible and skull. Signs include pain upon opening the mouth.
The source of the disease is unknown, with the Environment Agency ruling out any chemical contamination in water supplies. Experts believe the disease is “very similar” to Alabama Rot, thought to be related to a toxin produced by E. Coli bacteria. However, no evidence of this has been found after no signs were shown on the infected dogs.
What to look for: The signs of obesity might seem obvious, but having regular weight checks is important in order to keep records of your dog’s weight over time. It is important to recognize your dog’s weight gain early to give him the best chance possible for recourse.
Granulomatous meningoencephalitis (GME) (including Pug Dog encephalitis and other noninfectious causes of meningoencephalitis) is an inflammatory disease of the central nervous system of dogs. It is a form of meningoencephalitis. The disease is more common in female toy dogs of young and middle age.
Wash your hands with soap and running water after contact with dogs, dog saliva, or dog stool. Be sure to assist children with handwashing. Thoroughly washing hands will reduce the risk of disease transmission to people.
Systemic lupus erythematosus (SLE)* is an immune system disease characterized by the presence of antibodies to nucleic acid and/or antibodies to red blood cells, platelets, lymphocytes, clotting factors, and thyroglobulin. The disease can result in deposition of immune complexes or autoimmune disease. Immune complex deposition can cause vasculitis, meningitis, neuritis, and joint and skin disease. The most commons signs are hemolytic anemia or thrombocytopenia.
Developmental orthopedic diseases include panosteitis and hypertrophic osteodystrophy. Panosteitis occurs in large and giant breed dogs usually between the age of five and fourteen months and manifests as fever, pain, and shifting leg lameness. Hypertrophic osteodystrophy is also seen in young large and giant breed dogs and is characterized by pain, lameness, fever, and swelling of the long bone metaphysis.
Rarely, Capnocytophaga can spread to people through bites, scratches, or close contact from a dog or cat and cause illness. Most people who have contact with a dog or cat do not become sick. People with weakened immune systems who have difficulty fighting off infections (for example, people with cancer or those taking certain medications such as steroids) are at greater risk of becoming ill.
Patent ductus arteriosus* is one of the most common congenital heart defect in dogs around the world. It is inherited in toy and miniature Poodles, and seen commonly in German Shepherds, Pomeranians, Bichon Frises, and Malteses. Signs include a continuous heart murmur, bounding (strong) femoral pulse, tachypnea (increased breathing rate), dyspnea (labored breathing), and exercise intolerance.
Subaortic stenosis, or SAS, is a genetic ailment that causes a narrowing of the passage of blood between the heart and the aorta. This leads to heart problems and sometimes sudden death. It affects larger breeds such as the Newfoundland Dog and the Golden Retriever. In some dogs, such as collies, the blue merle or harlequin coloring is actually the heterozygote of a partially recessive gene preventing proper development of the nervous system; therefore, if two such dogs are mated, on the average one quarter of the puppies will have severe genetic defects in their nervous systems and sensory organs ranging from deafness to fatal flaws.
Diagnosis of canine parvovirus is based on symptoms, physical examination, and laboratory tests. In puppies and dogs that have not been vaccinated, CPV infection often is suspected when bloody diarrhea, loss of appetite, and vomiting develop suddenly. Physical examination may reveal signs of dehydration (e.g., lethargy, sunken eyes, dry gums, rapid heart rate, concentrated urine), fever, abdominal discomfort, swollen lymph nodes, and weight loss.
Although the name suggests otherwise, ringworm isn’t caused by a worm at all—but a fungus that can infect the skin, hair and nails. This highly contagious disease can lead to patchy areas of hair loss on a dog and can spread to other animals—and to humans, too.
Jump up ^ Eirmann, L (2017). “Chapter 167: Antioxidants, nutraceuticals, probiotics, and nutritional supplements”. In Ettinger, SJ; Feldman, EC; Cote, E. Textbook of Veterinary Internal Medicine (8th ed.). Elsevier Health Sciences. ISBN 9780323312394.
How to treat: Prevention is your best option. It starts with getting your dog shots every year. You should also monitor your dog’s activity to make sure he isn’t interacting with rabies infected animals in the wild. If you suspect that your dog has rabies, call Animal Control immediately and avoid your dog as much as possible.